Mitochondrial DNA drives noncanonical inflammation activation via cGAS-STING signaling pathway in retinal microvascular endothelial cells.-论文-万方医学网

作者： Yue,Guo ^[1] ; Ruiping,Gu ^[1] ; Dekang,Gan ^[1] ; Fangyuan,Hu ^[2] ; Gang,Li ^[2] ; Gezhi,Xu ^[3]

作者单位： Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, 200031, China. ^[1] Eye Institute, Eye and ENT Hospital of Fudan University, Shanghai, 200031, China. ^[2] Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, 200031, China. xugezhi@sohu.com. ^[3] Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, 200031, China. xugezhi@sohu.com. ^[4] Key Laboratory of Myopia of State Health Ministry, Shanghai, 200031, China. xugezhi@sohu.com. ^[5]

主题词衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);动物(Animals);细胞核(Cell Nucleus);细胞因子类(Cytokines);胞质溶胶(Cytosol);DNA, 线粒体(DNA, Mitochondrial);内质网(Endoplasmic Reticulum);内皮细胞(Endothelial Cells);高尔基体(Golgi Apparatus);炎症(Inflammation);炎症介导素类(Inflammation Mediators);胞间黏附分子1(Intercellular Adhesion Molecule-1);干扰素调节因子3(Interferon Regulatory Factor-3);膜蛋白质类(Membrane Proteins);微血管(Microvessels);NF-κB(NF-kappa B);核苷酸基转移酶类(Nucleotidyltransferases);磷酰化(Phosphorylation);蛋白质转运(Protein Transport);RNA, 信使(RNA, Messenger);大鼠(Rats);视网膜(Retina);信号传导(Signal Transduction)

DOI 10.1186/s12964-020-00637-3

PMID 33115500

发布时间 2021-12-04

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Mitochondrial DNA drives noncanonical inflammation activation via cGAS-STING signaling pathway in retinal microvascular endothelial cells.

Cell communication and signaling

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Cell communication and signaling

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Mitochondrial DNA drives noncanonical inflammation activation via cGAS-STING signaling pathway in retinal microvascular endothelial cells.

Cell communication and signaling

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Cell communication and signaling

相关期刊

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