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首页> Nature communications> Nuclear gene proximity and protein interactions shape transcript covariations in mammalian single cells.

Nuclear gene proximity and protein interactions shape transcript covariations in mammalian single cells.

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作者： Marcel,Tarbier ^[1] ; Sebastian D,Mackowiak ^[1] ; João,Frade ^[2] ; Silvina,Catuara-Solarz ^[2] ; Inna,Biryukova ^[1] ; Eleni,Gelali ^[3] ; Diego Bárcena,Menéndez ^[2] ; Luis,Zapata ^[2] ; Stephan,Ossowski ^[4] ; Magda,Bienko ^[2] ; Caroline J,Gallant ^[5] ; Marc R,Friedländer ^[6]

作者单位： Science for Life Laboratory, Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden. ^[1] Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona, Spain. ^[2] Science for Life Laboratory, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden. ^[3] Center for Evolution and Cancer, The Institute of Cancer Research, London, UK. ^[4] Department of Experimental and Health Sciences, University Pompeu Fabra, Barcelona, Spain. ^[5] Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany. ^[6] Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden. ^[7] Science for Life Laboratory, Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden. marc.friedlander@scilifelab.se. ^[8]

主题词动物(Animals);细胞系(Cell Line);细胞核(Cell Nucleus);基因表达谱(Gene Expression Profiling);基因表达调控(Gene Expression Regulation);基因敲除技术(Gene Knockout Techniques);基因调控网络(Gene Regulatory Networks);遗传变异(Genetic Variation);小鼠(Mice);微RNAs(MicroRNAs);核糖核酸酶Ⅲ(Ribonuclease III);单细胞分析(Single-Cell Analysis);转录因子(Transcription Factors)

DOI 10.1038/s41467-020-19011-5

PMID 33116115

发布时间 2020-11-12

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Nature communications

Nature communications

2020年11卷1期

5445页

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Nature communications

2020年11卷1期

5445页

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