Local application of curcumin-loaded nanoparticles as an adjunct to scaling and root planing in periodontitis: Randomized, placebo-controlled, double-blind split-mouth clinical trial.

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作者： Cindy Grace,Pérez-Pacheco ^[1] ; Natalie Ap Rodrigues,Fernandes ^[1] ; Fernando Lucas,Primo ^[2] ; Antonio Claudio,Tedesco ^[3] ; Emily,Bellile ^[4] ; Belen,Retamal-Valdes ^[5] ; Magda,Feres ^[5] ; Morgana Rodrigues,Guimarães-Stabili ^[1] ; Carlos,Rossa ^[6]

作者单位： Department of Diagnosis and Surgery, School of Dentistry at Araraquara, Sao Paulo State University (UNESP), Araraquara, SP, Brazil. ^[1] Department of Bioprocess and Biotechnology, Faculty of Pharmaceutical Sciences of Araraquara, Sao Paulo State University (UNESP), Araraquara, SP, Brazil. ^[2] Department of Chemistry, Center of Nanotechnology and Tissue Engineering- Photobiology and Photomedicine Research Group, Faculty of Philosophy, Sciences and Letters of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, SP, Brazil. ^[3] Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA. ^[4] Department of Periodontology and Oral Implantology, Dental Research Division, Universidade de Guarulhos - UNG, Sao Paulo, SP, Brazil. ^[5] Department of Diagnosis and Surgery, School of Dentistry at Araraquara, Sao Paulo State University (UNESP), Araraquara, SP, Brazil. c.rossa@unesp.br. ^[6]

关键词 Curcumin Dental Scaling Nanoparticles Periodontitis