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Behavioral, axonal, and proteomic alterations following repeated mild traumatic brain injury: Novel insights using a clinically relevant rat model.

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第一作者： Louise,Pham

第一单位： Department of Physiology, Anatomy and Microbiology, School of Life Sciences, La Trobe University, Melbourne, VIC 3086, Australia.

作者： Louise,Pham ^[1] ; David K,Wright ^[2] ; William T,O'Brien ^[2] ; Jesse,Bain ^[2] ; Cheng,Huang ^[3] ; Mujun,Sun ^[2] ; Pablo M,Casillas-Espinosa ^[4] ; Anup D,Shah ^[5] ; Ralf B,Schittenhelm ^[3] ; Christopher G,Sobey ^[1] ; Rhys D,Brady ^[4] ; Terence J,O'Brien ^[6] ; Richelle,Mychasiuk ^[2] ; Sandy R,Shultz ^[6] ; Stuart J,McDonald ^[7]

作者单位： Department of Physiology, Anatomy and Microbiology, School of Life Sciences, La Trobe University, Melbourne, VIC 3086, Australia. ^[1] Department of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC 3004, Australia. ^[2] Monash Proteomics & Metabolomics Facility, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, VIC 3800, Australia. ^[3] Department of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC 3004, Australia; Department of Medicine, The University of Melbourne, Melbourne, VIC 3052, Australia. ^[4] Monash Proteomics & Metabolomics Facility, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, VIC 3800, Australia; Monash Bioinformatics Platform, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, VIC 3800, Australia. ^[5] Department of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC 3004, Australia; Department of Neurology, The Alfred Hospital, Melbourne, VIC 3004, Australia; Department of Medicine, The University of Melbourne, Melbourne, VIC 3052, Australia. ^[6] Department of Physiology, Anatomy and Microbiology, School of Life Sciences, La Trobe University, Melbourne, VIC 3086, Australia; Department of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC 3004, Australia. Electronic address: stuart.mcdonald@monash.edu. ^[7]

关键词 Axonal injury Biomarkers Concussion MRI Neurofilament light