Synthesis and biological evaluation of novel flexible nucleoside analogues that inhibit flavivirus replication in vitro.

导出 OA

翻译打印收藏纠错

第一作者： Joy E,Thames

第一单位： Department of Chemistry and Biochemistry, University of Maryland, Baltimore County, Baltimore, MD, USA.

作者： Joy E,Thames ^[1] ; Charles D,Waters ^[1] ; Coralie,Valle ^[2] ; Marcella,Bassetto ^[3] ; Wahiba,Aouadi ^[2] ; Baptiste,Martin ^[2] ; Barbara,Selisko ^[2] ; Arissa,Falat ^[1] ; Bruno,Coutard ^[4] ; Andrea,Brancale ^[5] ; Bruno,Canard ^[2] ; Etienne,Decroly ^[2] ; Katherine L,Seley-Radtke ^[6]

作者单位： Department of Chemistry and Biochemistry, University of Maryland, Baltimore County, Baltimore, MD, USA. ^[1] AFMB-UMR7257, CNRS, Aix Marseille University, Marseille, France. ^[2] Department of Chemistry, College of Science, Swansea University, Swansea, UK. ^[3] Unité des Virus Émergents (UVE: Aix-Marseille Univ - IRD 190 - Inserm 1207 - IHU Méditerranée Infection), Marseille, France. ^[4] School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, UK. ^[5] Department of Chemistry and Biochemistry, University of Maryland, Baltimore County, Baltimore, MD, USA. Electronic address: kseley@umbc.edu. ^[6]

关键词 Acyclovir Dengue Flavivirus Fleximers Methyltransferase Nucleoside Yellow Fever Zika