Colon targeted delivery of niclosamide from β-cyclodextrin inclusion complex incorporated electrospun Eudragit® L100 nanofibers.

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第一作者： Ozlem,Coban

第一单位： Department of Pharmaceutical Technology, Faculty of Pharmacy, Karadeniz Technical University, Trabzon, 61080, Turkey.

作者： Ozlem,Coban ^[1] ; Zeynep,Aytac ^[2] ; Zehra Irem,Yildiz ^[2] ; Tamer,Uyar ^[3]

作者单位： Department of Pharmaceutical Technology, Faculty of Pharmacy, Karadeniz Technical University, Trabzon, 61080, Turkey. ^[1] Institute of Materials Science & Nanotechnology, UNAM-National Nanotechnology Research Center, Bilkent University, Ankara, 06800, Turkey. ^[2] Institute of Materials Science & Nanotechnology, UNAM-National Nanotechnology Research Center, Bilkent University, Ankara, 06800, Turkey; Department of Fiber Science & Apparel Design, College of Human Ecology, Cornell University, Ithaca, NY, 14853, USA. Electronic address: tu46@cornell.edu. ^[3]

关键词 Cyclodextrin Electrospinning Eudragit? L100 Nanofiber Niclosamide

主题词结肠(Colon);药物载体(Drug Carriers);纳米纤维(Nanofibers);氯硝柳胺(Niclosamide);聚甲基丙烯酸类(Polymethacrylic Acids);溶解度(Solubility);β环糊精类(beta-Cyclodextrins)

DOI 10.1016/j.colsurfb.2020.111391

PMID 33129100

发布时间 2021-06-17

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