Cyclic imine toxins survey in coastal european shellfish samples: Bioaccumulation and mode of action of 28-O-palmitoyl ester of pinnatoxin-G. first report of portimine-A bioaccumulation.

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作者： Rómulo,Aráoz ^[1] ; Paul,Barnes ^[2] ; Véronique,Séchet ^[3] ; Muriel,Delepierre ^[4] ; Sophie,Zinn-Justin ^[5] ; Jordi,Molgó ^[6] ; Armen,Zakarian ^[7] ; Philipp,Hess ^[3] ; Denis,Servent ^[6]

作者单位： Université Paris Saclay, CEA, INRAE, Département Médicaments et Technologies pour la Santé (DMTS), SIMoS, 91191 Gif-sur-Yvette, France; CNRS, ERL9004, 91191, Gif-sur-Yvette, France. Electronic address: romulo.araoz@cea.fr. ^[1] Agri-food and Biosciences Institute, Veterinary Science Division, Stoney Road, Belfast BT4 3SD, Northern Ireland, United Kingdom. ^[2] Ifremer, Centre Atlantique, Laboratoire Phycotoxines, 44311 Nantes Cedex, France. ^[3] Institut Pasteur, Department of Structural Biology and Chemistry CNRS, UMR3528, Paris France. ^[4] Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ Paris-Sud, Université Paris-Saclay, Gif- sur -Yvette Cedex, France. ^[5] Université Paris Saclay, CEA, INRAE, Département Médicaments et Technologies pour la Santé (DMTS), SIMoS, 91191 Gif-sur-Yvette, France; CNRS, ERL9004, 91191, Gif-sur-Yvette, France. ^[6] University California Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 United States. ^[7]

关键词 28-o-palmitoyl ester of pinnatoxin-G Cyclic imine toxins Microplate receptor-binding assay Nicotinic acetylcholine receptors Pinnatoxin-G Portimine-A Two-electrode voltage clamp electrophysiology