Path of Silibinin from diet to medicine: A dietary polyphenolic flavonoid having potential anti-cancer therapeutic significance.

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第一作者： Hardeep Singh,Tuli

第一单位： Department of Biotechnology, Maharishi Markandeshwar (Deemed to be University), Mullana-Ambala, 133 207, Haryana, India.

作者： Hardeep Singh,Tuli ^[1] ; Sonam,Mittal ^[2] ; Diwakar,Aggarwal ^[1] ; Gaurav,Parashar ^[1] ; Nidarshana Chaturvedi,Parashar ^[1] ; Sushil Kumar,Upadhyay ^[1] ; Tushar Singh,Barwal ^[3] ; Aklank,Jain ^[3] ; Ginpreet,Kaur ^[4] ; Raj,Savla ^[4] ; Katrin,Sak ^[5] ; Manoj,Kumar ^[6] ; Mehmet,Varol ^[7] ; Ashif,Iqubal ^[8] ; Anil Kumar,Sharma ^[9]

作者单位： Department of Biotechnology, Maharishi Markandeshwar (Deemed to be University), Mullana-Ambala, 133 207, Haryana, India. ^[1] School of Biotechnology, Jawaharlal Nehru University, New Delhi, India. ^[2] Department of Zoology, Central University of Punjab, Bathinda, 151 001, Punjab, India. ^[3] Department of Pharmacology, Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management, SVKM's, NMIMS, Mumbai, 400 056, Maharastra, India. ^[4] NGO Praeventio, Tartu, 50407, Estonia. ^[5] Department of Chemistry, Maharishi Markandeshwar University, Sadopur, India. ^[6] Department of Molecular Biology and Genetics, Faculty of Science, Mugla Sitki Kocman University, Mugla, TR48000, Turkey. ^[7] Department of Pharmacology, School of Pharmaceutical Education and Research (Formerly Faculty of Pharmacy), Jamia Hamdard (Deemed to be University), Delhi, India. ^[8] Department of Biotechnology, Maharishi Markandeshwar (Deemed to be University), Mullana-Ambala, 133 207, Haryana, India. Electronic address: anibiotech18@gmail.com. ^[9]

关键词 Anti-angiogenesis Anti-metastasis Apoptosis Cell cycle arrest Clinical studies Flavonolignans Silibinin

主题词动物(Animals);抗肿瘤药, 植物(Antineoplastic Agents, Phytogenic);人类(Humans);肿瘤(Neoplasms)

DOI 10.1016/j.semcancer.2020.09.014

PMID 33130037

发布时间 2022-03-04

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