Titin-truncating mutations associated with dilated cardiomyopathy alter length-dependent activation and its modulation via phosphorylation.-论文-万方医学网

作者： Petr G,Vikhorev ^[1] ; Natalia N,Vikhoreva ^[2] ; WaiChun,Yeung ^[1] ; Amy,Li ^[3] ; Sean,Lal ^[4] ; Cristobal G,Dos Remedios ^[5] ; Cheavar A,Blair ^[6] ; Maya,Guglin ^[6] ; Kenneth S,Campbell ^[6] ; Magdi H,Yacoub ^[1] ; Pieter,de Tombe ^[1] ; Steven B,Marston ^[2]

作者单位： National Heart and Lung Institute, Imperial College London, Du Cane Road, London W12 0NN, UK. ^[1] Heart Science Centre, Magdi Yacoub Institute, Harefield Hospital, London UB9 6JH, UK. ^[2] Department of Pharmacy and Biomedical Sciences, La Trobe University, Bendigo, VIC 3550, Australia. ^[3] School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, NSW 2006, Australia. ^[4] Division of Molecular Cardiology and Biophysics, Victor Chang Cardiac Research Institute, Darlinghurst, NSW 2010, Australia. ^[5] Division of Cardiovascular Medicine, Department of Physiology, University of Kentucky, Lexington, KY, USA. ^[6] Department of Physiology and Biophysics, University of Illinois at Chicago, Chicago, IL, USA. ^[7]

主题词成年人(Adult);心肌病, 扩张型(Cardiomyopathy, Dilated);载体蛋白质类(Carrier Proteins);环AMP依赖性蛋白激酶类(Cyclic AMP-Dependent Protein Kinases);女(雌)性(Female);疾病遗传易感性(Genetic Predisposition to Disease);人类(Humans);动力学(Kinetics);男(雄)性(Male);中年人(Middle Aged);突变(Mutation);心肌收缩(Myocardial Contraction);肌细胞, 心脏(Myocytes, Cardiac);肌原纤维(Myofibrils);表型(Phenotype);磷蛋白磷酸酶类(Phosphoprotein Phosphatases);磷酰化(Phosphorylation);肌钙蛋白I(Troponin I);病毒蛋白质类(Viral Proteins);青年人(Young Adult)

DOI 10.1093/cvr/cvaa316

PMID 33135063

发布时间 2022-03-07

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Titin-truncating mutations associated with dilated cardiomyopathy alter length-dependent activation and its modulation via phosphorylation.

Cardiovascular research

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Cardiovascular research

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Titin-truncating mutations associated with dilated cardiomyopathy alter length-dependent activation and its modulation via phosphorylation.

Cardiovascular research

相似文献

Cardiovascular research

相关期刊

检索历史清除