Broad phenotypic spectrum of germ line 7p12.1 microdeletions encompassing the IKZF1 gene includes predisposition to acute lymphoblastic leukemia.

导出 LinkOut

翻译打印收藏纠错

作者： Agata,Pastorczak ^[1] ; Anna,Hogendorf ^[2] ; Zuzanna,Urbanska ^[1] ; Edyta,Budzynska ^[3] ; Dorota,Jesionek-Kupnicka ^[4] ; Agnieszka,Gach ^[5] ; Wanda,Hawula ^[5] ; Robert,Smigiel ^[6] ; Pawel,Skiba ^[7] ; Maria,Sasiadek ^[7] ; Monika,Lejman ^[8] ; Maria,Constatinou ^[3] ; Beata S,Lipska-Ziętkiewicz ^[9] ; Wojciech,Mlynarski ^[10]

作者单位： Department of Pediatrics, Oncology and Hematology, Medical University of Lodz, Lodz, Poland. ^[1] Department of Pediatrics, Diabetology, Endocrinology and Nephrology, Medical University of Lodz, Lodz, Poland. ^[2] Department of Clinical Genetics, Medical University of Lodz, Lodz, Poland. ^[3] Department of Pathology, Chair of Oncology, Medical University of Lodz, Lodz, Poland. ^[4] Department of Medical Genetics, Polish Mother's Memorial Hospital-Research Institute, Lodz, Poland. ^[5] Department of Pediatrics, Division of Propaedeutic Pediatrics and Rare Disorders, Wroclaw Medical University, Wroclaw, Poland. ^[6] Department of Genetics, Wroclaw Medical University, Wroclaw, Poland. ^[7] Laboratory of Genetic Diagnostics, Medical University of Lublin, Lublin, Poland. ^[8] Centre for Rare Diseases, Medical University of Gdansk, Gdansk, Poland. ^[9] Clinial Genetics Unit, Department of Biology and Medical Genetics, Medical University of Gdansk, Gdansk, Poland. ^[10]

关键词 IKZF1 acute lymphoblastic leukemia genetic predisposition microdeletion