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eIF4E S209 phosphorylation licenses myc- and stress-driven oncogenesis.

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第一作者： Hang,Ruan

第一单位： Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, United States.;UPMC Hillman Cancer Center, Pittsburgh, United States.

作者： Hang,Ruan ^[1] ; Xiangyun,Li ^[2] ; Xiang,Xu ^[3] ; Brian J,Leibowitz ^[1] ; Jingshan,Tong ^[4] ; Lujia,Chen ^[5] ; Luoquan,Ao ^[3] ; Wei,Xing ^[3] ; Jianhua,Luo ^[6] ; Yanping,Yu ^[6] ; Robert E,Schoen ^[7] ; Nahum,Sonenberg ^[8] ; Xinghua,Lu ^[5] ; Lin,Zhang ^[4] ; Jian,Yu ^[1]

作者单位： Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, United States.;UPMC Hillman Cancer Center, Pittsburgh, United States. ^[1] Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, United States.;UPMC Hillman Cancer Center, Pittsburgh, United States.;Department of Stem cell and regenerative medicine, Daping Hospital, Army Medical University, Chongqing, China. ^[2] Department of Stem cell and regenerative medicine, Daping Hospital, Army Medical University, Chongqing, China.;Central laboratory, State key laboratory of trauma, burn and combined Injury, Daping Hospital, Chongqing, China. ^[3] UPMC Hillman Cancer Center, Pittsburgh, United States.;Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, United States. ^[4] UPMC Hillman Cancer Center, Pittsburgh, United States.;Department of Biomedical informatics, University of Pittsburgh School of Medicine, Pittsburgh, United States. ^[5] Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, United States. ^[6] Departments of Medicine and Epidemiology, University of Pittsburgh, Pittsburgh, United States. ^[7] Department of Biochemistry, Goodman Cancer Research Centre, McGill University, Montreal, Canada. ^[8]

关键词 KRAS Myc cancer biology colon cancer eIF4E S209 glutamine human mouse the integrated stress response