CRISPR-Cas adaptive immune systems in Sulfolobales: genetic studies and molecular mechanisms.

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作者： Zhenxiao,Yu ^[1] ; Suping,Jiang ^[1] ; Yuan,Wang ^[2] ; Xuhui,Tian ^[1] ; Pengpeng,Zhao ^[2] ; Jianan,Xu ^[1] ; Mingxia,Feng ^[2] ; Qunxin,She ^[1]

作者单位： CRISPR and Archaea Biology Research Center, State Key Laboratory of Microbial Technology, Shandong University, Qingdao, 266237, China. ^[1] State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China. ^[2] CRISPR and Archaea Biology Research Center, State Key Laboratory of Microbial Technology, Shandong University, Qingdao, 266237, China. shequnxin@sdu.edu.cn. ^[3]

关键词 CRISPR-Cas PAM-dependent DNA interference RNA-activated Cas10 activities Sulfolobales adaptation anti-CRISPR cOA signaling crRNA processing spatiotemporal regulation

主题词适应性免疫(Adaptive Immunity);DNA, 古细菌(DNA, Archaeal);基因, 古细菌(Genes, Archaeal);模型, 生物学(Models, Biological);RNA, 古细菌(RNA, Archaeal);硫化叶菌目(Sulfolobales);转录, 遗传(Transcription, Genetic)

DOI 10.1007/s11427-020-1745-0

PMID 33140167

发布时间 2021-12-27

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Science China. Life sciences

2021年64卷5期

678-696页

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CRISPR-Cas adaptive immune systems in Sulfolobales: genetic studies and molecular mechanisms.

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CRISPR-Cas adaptive immune systems in Sulfolobales: genetic studies and molecular mechanisms.

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