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Low Shear Stress Increases Recombinant Protein Production and High Shear Stress Increases Apoptosis in Human Cells.

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第一作者： Caijuan,Zhan

第一单位： KTH - Cell Technology Group (CETEG), Department of Industrial Biotechnology, 106 91, Stockholm, Sweden.;Wallenberg Centre for Protein Research (WCPR), 106 91 Stockholm, Sweden.;AdBIOPRO, Competence Centre for Advanced Bioproduction by Continuous Processing, Stockholm, Sweden.

作者： Caijuan,Zhan ^[1] ; Gholamreza,Bidkhori ^[2] ; Hubert,Schwarz ^[1] ; Magdalena,Malm ^[3] ; Aman,Mebrahtu ^[3] ; Ray,Field ^[4] ; Christopher,Sellick ^[4] ; Diane,Hatton ^[4] ; Paul,Varley ^[4] ; Adil,Mardinoglu ^[2] ; Johan,Rockberg ^[5] ; Veronique,Chotteau ^[1]

作者单位： KTH - Cell Technology Group (CETEG), Department of Industrial Biotechnology, 106 91, Stockholm, Sweden.;Wallenberg Centre for Protein Research (WCPR), 106 91 Stockholm, Sweden.;AdBIOPRO, Competence Centre for Advanced Bioproduction by Continuous Processing, Stockholm, Sweden. ^[1] Science for Life Laboratory, KTH - Royal Institute of Technology, 171 21, Stockholm, Sweden. ^[2] KTH - Royal Institute of Technology, Department of Protein Science, 106 91 Stockholm, Sweden.;Wallenberg Centre for Protein Research (WCPR), 106 91 Stockholm, Sweden. ^[3] BioPharmaceutical Development, AstraZeneca, Cambridge, UK. ^[4] KTH - Royal Institute of Technology, Department of Protein Science, 106 91 Stockholm, Sweden.;Wallenberg Centre for Protein Research (WCPR), 106 91 Stockholm, Sweden.;AdBIOPRO, Competence Centre for Advanced Bioproduction by Continuous Processing, Stockholm, Sweden. ^[5]

关键词 Bioengineering Biophysics Cell Biology

DOI 10.1016/j.isci.2020.101653

PMID 33145483

发布时间 2023-11-12

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Low Shear Stress Increases Recombinant Protein Production and High Shear Stress Increases Apoptosis in Human Cells.

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