N- and S-oxygenation activity of truncated human flavin-containing monooxygenase 3 and its common polymorphic variants.

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作者： Stefania,Bortolussi ^[1] ; Gianluca,Catucci ^[2] ; Gianfranco,Gilardi ^[3] ; Sheila J,Sadeghi ^[4]

作者单位： Department of Life Sciences and Systems Biology, University of Torino, Italy; School of Health, Sport and Bioscience, University of East London, UK. Electronic address: s.bortolussi@uel.ac.uk. ^[1] Department of Life Sciences and Systems Biology, University of Torino, Italy. Electronic address: gianluca.catucci@unito.it. ^[2] Department of Life Sciences and Systems Biology, University of Torino, Italy. Electronic address: gianfranco.gilardi@unito.it. ^[3] Department of Life Sciences and Systems Biology, University of Torino, Italy. Electronic address: sheila.sadeghi@unito.it. ^[4]

关键词 Biocatalysis Drug metabolism Flavin-containing monooxygenase Flavoprotein Polymorphic variants Truncation

主题词人类(Humans);模型, 分子(Models, Molecular);氧化还原(Oxidation-Reduction);氧(Oxygen);氧合酶类(Oxygenases);多态现象, 遗传(Polymorphism, Genetic);蛋白质构象(Protein Conformation)

DOI 10.1016/j.abb.2020.108663

PMID 33152328

发布时间 2021-02-01

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