PWD/Ph-Encoded Genetic Variants Modulate the Cellular Wnt/β-Catenin Response to Suppress <i>Apc</i><sup>Min</sup>-Triggered Intestinal Tumor Formation.

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作者： Alexandra L,Farrall ^[1] ; Matthias,Lienhard ^[2] ; Christina,Grimm ^[1] ; Heiner,Kuhl ^[1] ; Susanna H M,Sluka ^[3] ; Marta,Caparros ^[1] ; Jiri,Forejt ^[4] ; Bernd,Timmermann ^[1] ; Ralf,Herwig ^[1] ; Bernhard G,Herrmann ^[5] ; Markus,Morkel ^[1]

作者单位： Max Planck Institute for Molecular Genetics, Berlin, Germany. ^[1] College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia. ^[2] Department of Translational Epigenetics and Tumor Genetics, University Hospital Cologne, Cologne, Germany. ^[3] Leibniz-Institute of Freshwater Ecology and Inland Fisheries, Department of Ecophysiology and Aquaculture, Berlin, Germany. ^[4] Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Vestec, Prague, Czech Republic. ^[5] Max Planck Institute for Molecular Genetics, Berlin, Germany. Markus.Morkel@charite.de herrmann@molgen.mpg.de. ^[6] Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute for Medical Genetics, Berlin, Germany. ^[7] Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pathology, Berlin, Germany. Markus.Morkel@charite.de herrmann@molgen.mpg.de. ^[8]