Sodium P-aminosalicylic Acid Inhibits Manganese-Induced Neuroinflammation in BV2 Microglial Cells via NLRP3-CASP1 Inflammasome Pathway.

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作者： Yuanyuan,Fang ^[1] ; Dongjie,Peng ^[2] ; Yuan,Liang ^[1] ; Lili,Lu ^[2] ; Junyan,Li ^[1] ; Lin,Zhao ^[2] ; Shiyan,Ou ^[1] ; Shaojun,Li ^[2] ; Michael,Aschner ^[1] ; Yueming,Jiang ^[2]

作者单位： Department of Toxicology, School of Public Health, Guangxi Medical University, No. 22, Shuang-yong Rd, Nanning, 530021, Guangxi, China. ^[1] Guangxi Colleges and Universities Key Laboratory of Prevention and Control of Highly Prevalent Diseases, Guangxi Medical University, Nanning, China. ^[2] Albert Einstein College of Medicine, Bronx, NY, 10461, USA. ^[3] Department of Toxicology, School of Public Health, Guangxi Medical University, No. 22, Shuang-yong Rd, Nanning, 530021, Guangxi, China. ymjianggxmu@163.com. ^[4] Guangxi Colleges and Universities Key Laboratory of Prevention and Control of Highly Prevalent Diseases, Guangxi Medical University, Nanning, China. ymjianggxmu@163.com. ^[5]

关键词 CASP1 inflammasome Manganese NLRP3 inflammasome NLRP3-CASP1 pathway Neuroinflammation Sodium para-aminosalicylate

主题词氨基水杨酸(Aminosalicylic Acid);炎性体(Inflammasomes);锰(Manganese);小神经胶质细胞(Microglia);药用制剂(Pharmaceutical Preparations);钠(Sodium)

DOI 10.1007/s12011-020-02471-7

PMID 33156491

发布时间 2021-07-07

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