首页> European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences> Inhibition of NLRP3-inflammasome mediated IL-1β release by phenylpropanoic acid derivatives: in-silico and in-vitro approach.

Inhibition of NLRP3-inflammasome mediated IL-1β release by phenylpropanoic acid derivatives: in-silico and in-vitro approach.

导出 LinkOut

翻译打印收藏纠错

第一作者： Manas,Kinra

第一单位： Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, India.

作者： Manas,Kinra ^[1] ; Alex,Joseph ^[2] ; Madhavan,Nampoothiri ^[1] ; Devinder,Arora ^[3] ; Jayesh,Mudgal ^[4]

作者单位： Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, India. ^[1] Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, India. ^[2] Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, India; School of Pharmacy and Pharmacology, MHIQ, QUM Network, Griffith University, Queensland, Australia. ^[3] Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, India. Electronic address: jayesh.mudgal@manipal.edu. ^[4]

关键词 NLRP3 inflammasome, caspase-1, phenylpropanoic acid interleukin-1β pyroptosis

医学主题词细胞因子类(Cytokines);炎性体(Inflammasomes);白细胞介素1β(Interleukin-1beta)

DOI 10.1016/j.ejps.2020.105637

PMID 33171231

发布时间 2021-06-21

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交