换一批Multi-ancestry genetic study in 5,876 patients identifies an association between excitotoxic genes and early outcomes after acute ischemic stroke.
第一作者：
Laura,Ibanez
第一单位：
Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid Avenue, Saint Louis (63110), Missouri, US.;NeuroGenomics and Informatics, Washington University School of Medicine, 425 S. Euclid Avenue, Saint Louis (63110), Missouri, US.
作者：
Laura,Ibanez [1]
;
Laura,Heitsch [2]
;
Caty,Carrera [3]
;
Fabiana H G,Farias [1]
;
Rajat,Dhar [4]
;
John,Budde [1]
;
Kristy,Bergmann [1]
;
Joseph,Bradley [1]
;
Oscar,Harari [5]
;
Chia-Ling,Phuah [4]
;
Robin,Lemmens [6]
;
Alessandro A Viana Oliveira,Souza [7]
;
Francisco,Moniche [8]
;
Antonio,Cabezas-Juan [9]
;
Juan Francisco,Arenillas [10]
;
Jerzy,Krupinksi [11]
;
Natalia,Cullell [12]
;
Nuria,Torres-Aguila [12]
;
Elena,Muiño [13]
;
Jara,Cárcel-Márquez [13]
;
Joan,Marti-Fabregas [13]
;
Raquel,Delgado-Mederos [13]
;
Rebeca,Marin-Bueno [13]
;
Alejandro,Hornick [14]
;
Cristofol,Vives-Bauza [15]
;
Rosa Diaz,Navarro [16]
;
Silvia,Tur [16]
;
Carmen,Jimenez [16]
;
Victor,Obach [17]
;
Tomas,Segura [18]
;
Gemma,Serrano-Heras [18]
;
Jong-Won,Chung [19]
;
Jaume,Roquer [20]
;
Carol,Soriano-Tarraga [21]
;
Eva,Giralt-Steinhauer [20]
;
Marina,Mola-Caminal [22]
;
Joanna,Pera [23]
;
Katarzyna,Lapicka-Bodzioch [23]
;
Justyna,Derbisz [23]
;
Antoni,Davalos [24]
;
Elena,Lopez-Cancio [25]
;
Lucia,Muñoz [24]
;
Turgut,Tatlisumak [26]
;
Carlos,Molina [3]
;
Marc,Ribo [3]
;
Alejandro,Bustamante [24]
;
Tomas,Sobrino [27]
;
Jose,Castillo-Sanchez [27]
;
Francisco,Campos [27]
;
Emilio,Rodriguez-Castro [27]
;
Susana,Arias-Rivas [27]
;
Manuel,Rodríguez-Yáñez [27]
;
Christina,Herbosa [4]
;
Andria L,Ford [28]
;
Antonio,Arauz [29]
;
Iscia,Lopes-Cendes [7]
;
Theodore,Lowenkopf [30]
;
Miguel A,Barboza [31]
;
Hajar,Amini [32]
;
Boryana,Stamova [32]
;
Bradley P,Ander [32]
;
Frank R,Sharp [32]
;
Gyeong Moon,Kim [19]
;
Oh Young,Bang [19]
;
Jordi,Jimenez-Conde [20]
;
Agnieszka,Slowik [23]
;
Daniel,Stribian [33]
;
Ellen A,Tsai [34]
;
Linda C,Burkly [35]
;
Joan,Montaner [36]
;
Israel,Fernandez-Cadenas [37]
;
Jin-Moo,Lee [38]
;
Carlos,Cruchaga [39]
作者单位：
Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid Avenue, Saint Louis (63110), Missouri, US.;NeuroGenomics and Informatics, Washington University School of Medicine, 425 S. Euclid Avenue, Saint Louis (63110), Missouri, US.
[1]
Department of Neurology, Washington University School of Medicine, 660 S. Euclid Avenue; Campus Box 8111; Saint Louis (63110), Missouri, US.;Emergency Medicine, Washington University School of Medicine, 660 S. Euclid Avenue; Campus Box 8072; Saint Louis (63110), Missouri, US.
[2]
Stroke Unit, Vall d'Hebron University Hospital, Universitat de Barcelona, Passeig de la Vall d'Hebron, 1198; Barcelona (08035), Spain.
[3]
Department of Neurology, Washington University School of Medicine, 660 S. Euclid Avenue; Campus Box 8111; Saint Louis (63110), Missouri, US.
[4]
Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid Avenue, Saint Louis (63110), Missouri, US.;NeuroGenomics and Informatics, Washington University School of Medicine, 425 S. Euclid Avenue, Saint Louis (63110), Missouri, US.;The Charles F. and Joanne Knight Alzheimer Disease Research Center, Washington University School of Medicine, 4488 Forest Park Avenue; Saint Louis (63110), Missouri, US.;Department of Neuroscience, Katholieke Universiteit Leuven, Campus Gasthuisberg O&N2; Herestraat 49 box 1021; Leuven (BE-3000), Belgium.
[5]
Department of Neuroscience, Katholieke Universiteit Leuven, Campus Gasthuisberg O&N2; Herestraat 49 box 1021; Leuven (BE-3000), Belgium.
[6]
Department of Neurology, School of Medical Sciences, University of Campinas (UNICAMP), R. Tessalia Viera de Camargo, 126; Cidade Universitaria, Campinas (13083-887), Brazil.;Brazilian Institute of Neuroscience and Neurotecnology (BRAINN), R. Tessalia Viera de Camargo, 126; Cidade Universitaria, Campinas (13083-887), Brazil.
[7]
Department of neurology, Hospital Virgen del Rocio, University of Seville, Avenida Manuel Siurot, s/n; Seville (41013), Spain.
[8]
Department of neurology, Hospital Virgen del Rocio, University of Seville, Avenida Manuel Siurot, s/n; Seville (41013), Spain.;Hospital Virgen de la Macarena, University of Seville, Calle Dr. Fedriani, 3; Seville (41009), Spain.
[9]
Department of Neurology, Hospital Clinico Universitario Valladolid, Valladolid University, Avenida Ramon y Cajal, 3; Valladolid (47003), Spain.
[10]
Department of Neurology, Mutua Terrassa University Hospital, Universitat de Barcelona, Plaça del Dr. Robert, 5; Terrassa (08221), Spain.;Fundacio Docencia i Recerca Mutua Terrassa, Universitat de Barcelona, Carrer Sant Antoni, 19; Terrassa (08221), Spain.
[11]
Fundacio Docencia i Recerca Mutua Terrassa, Universitat de Barcelona, Carrer Sant Antoni, 19; Terrassa (08221), Spain.;Department of Neurology, Hospital de la Santa Creu i Sant Pau, Universitat Autonoma de Barcelona, Carrer de Sant Quinti, 89; Barcelona (08041), Spain.
[12]
Department of Neurology, Hospital de la Santa Creu i Sant Pau, Universitat Autonoma de Barcelona, Carrer de Sant Quinti, 89; Barcelona (08041), Spain.
[13]
Department of Neurology, Southern Illinois Healthcare Memorial Hospital of Carbondale, 405 W Jackson Street, Carbondale (62901), Illinois, US.
[14]
Department of Biology, Universitat de les Illes Balears, Carretera de Valldemossa, km 7,5, Palma (07122), Spain.
[15]
Department of Neurology, Hospital Universitari Son Espases, Universitat de les Illes Balears, Carretera de Valldemossa, 79, Palma (07120), Spain.
[16]
Department of Neurology, Hospital Clinic de Barcelona, Universitat de Barcelona, Carrer Villarroel, 170, Barcelona (08036), Spain.
[17]
Research Unit, Complejo Hospitalario Universitario de Albacete. Calle Laurel s/n. Albacete (02008), Spain.
[18]
Department of Neurology, Samsung Medical Center, 81 Irwon-ro, Gangnam-gu, Seoul, South Korea.
[19]
Neurovascular Research Group, Institut Hospital del Mar de Investigations Mediques, Passeig Maritim, 25-29, Barcelona (08003), Spain.
[20]
Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid Avenue, Saint Louis (63110), Missouri, US.;NeuroGenomics and Informatics, Washington University School of Medicine, 425 S. Euclid Avenue, Saint Louis (63110), Missouri, US.;Neurovascular Research Group, Institut Hospital del Mar de Investigations Mediques, Passeig Maritim, 25-29, Barcelona (08003), Spain.
[21]
Neurovascular Research Group, Institut Hospital del Mar de Investigations Mediques, Passeig Maritim, 25-29, Barcelona (08003), Spain.;Department of Surgical Sciences, Orthopedics, Uppsala University, Uppsala, 75185, Sweden.
[22]
Department of Neurology, Jagiellonian University, Golebia, 24, Krakow(31-007), Poland.
[23]
Department of Neurology, Hospital Germans Trias i Pujol, Universitat Autonoma de Barcelona, Carretera de Canyet, s/n; Badalona (08916), Spain.
[24]
Department of Neurology, Hospital Universitario Central de Asturias, Oviedo, Spain.
[25]
Department of Neurology, Sahlgrenska University Hospital, University of Gothenburg, Bla straket, 5; Gothenburg (413 45), Sweden.;Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.
[26]
Clinical Neurosciences Research Laboratory, Health Research Institute of Santiago de Compostela (IDIS), Avda. Travesa da Choupana s/n; Santiago de Compostela (15706), Spain.
[27]
Department of Neurology, Washington University School of Medicine, 660 S. Euclid Avenue; Campus Box 8111; Saint Louis (63110), Missouri, US.;Hope Center for Neurological Disorders, Washington University School of Medicine, 660 S. Euclid Avenue; Campus Box 8111; Saint Louis (63110), Missouri, US.;Department of Radiology, Washington University School of Medicine, 660 S. Euclid Avenue, Saint Louis (63110), Missouri, US.
[28]
Instituto Nacional de Neurologia y Neurocirurgia de Mexico, Avenida Insurgentes Sur 3877, Ciudad de Mexico (14269), Mexico.
[29]
Department of Neurology, Providence St. Vincent Medical Center, 9205 SW Barnes Rd, Portland (97225), Oregon, US.
[30]
Neurosciences Department, Hospital Rafael A. Calderon Guardia, Avenidas 7 y 9, calles 15 y 17, Aranjuez, San José, Costa Rica.
[31]
Department of Neurology and MIND Institute, University of California at Davis, 2825 5 street, Sacramento (95817), California, US.
[32]
Department of Neurology, Helsinki University Hospital, Haartmaninkatu 4 Rakennus 1, Helsinki (00290), Finland.
[33]
Translational Biology, Biogen, Inc, 115 Brodway, Cambridge (02142), Massachusetts, US.
[34]
Genetics and Neurodevelomental Disease Research Unit, Biogen, Inc, 115 Brodway, Cambridge (02142), Massachusetts, US.
[35]
Stroke Unit, Vall d'Hebron University Hospital, Universitat de Barcelona, Passeig de la Vall d'Hebron, 1198; Barcelona (08035), Spain.;Department of neurology, Hospital Virgen del Rocio, University of Seville, Avenida Manuel Siurot, s/n; Seville (41013), Spain.;Hospital Virgen de la Macarena, University of Seville, Calle Dr. Fedriani, 3; Seville (41009), Spain.
[36]
Stroke Unit, Vall d'Hebron University Hospital, Universitat de Barcelona, Passeig de la Vall d'Hebron, 1198; Barcelona (08035), Spain.;Department of Neurology, Hospital de la Santa Creu i Sant Pau, Universitat Autonoma de Barcelona, Carrer de Sant Quinti, 89; Barcelona (08041), Spain.
[37]
Department of Neurology, Washington University School of Medicine, 660 S. Euclid Avenue; Campus Box 8111; Saint Louis (63110), Missouri, US.;Hope Center for Neurological Disorders, Washington University School of Medicine, 660 S. Euclid Avenue; Campus Box 8111; Saint Louis (63110), Missouri, US.;Department of Radiology, Washington University School of Medicine, 660 S. Euclid Avenue, Saint Louis (63110), Missouri, US.;Department of Biomedical Engineering, Washington University School of Medicine, 660 S. Euclid Avenue, Saint Louis (63110), Missouri, US.;Stroke and Cerebrovascular Center, Washington University School of Medicine, One Barnes-Jewish Hospital Plaza, Saint Louis (63110), Missouri, US.
[38]
Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid Avenue, Saint Louis (63110), Missouri, US.;NeuroGenomics and Informatics, Washington University School of Medicine, 425 S. Euclid Avenue, Saint Louis (63110), Missouri, US.;Department of Neurology, Washington University School of Medicine, 660 S. Euclid Avenue; Campus Box 8111; Saint Louis (63110), Missouri, US.;Hope Center for Neurological Disorders, Washington University School of Medicine, 660 S. Euclid Avenue; Campus Box 8111; Saint Louis (63110), Missouri, US.;The Charles F. and Joanne Knight Alzheimer Disease Research Center, Washington University School of Medicine, 4488 Forest Park Avenue; Saint Louis (63110), Missouri, US.;Department of Genetics, Washington University School of Medicine, 4515 McKinley Ave, Saint Louis (63110), Missouri, US.
[39]
DOI
10.1101/2020.10.29.20222257
PMID
33173895
发布时间
2024-09-23
基金项目
U24 NS107230/NS/NINDS NIH HHS/United States
R01 NS085419/NS/NINDS NIH HHS/United States
R01 NS097000/NS/NINDS NIH HHS/United States
R01 NS106950/NS/NINDS NIH HHS/United States
R01 NS079153/NS/NINDS NIH HHS/United States
R01 NS075035/NS/NINDS NIH HHS/United States
K23 NS099487/NS/NINDS NIH HHS/United States
R01 NS101718/NS/NINDS NIH HHS/United States
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