首页> European urology> Advanced Prostate Cancer with ATM Loss: PARP and ATR Inhibitors.

Advanced Prostate Cancer with ATM Loss: PARP and ATR Inhibitors.

导出 LinkOut

翻译打印收藏纠错

第一作者： Antje,Neeb

第一单位： The Institute of Cancer Research, London, UK.

作者： Antje,Neeb ^[1] ; Nicolás,Herranz ^[2] ; Sara,Arce-Gallego ^[2] ; Susana,Miranda ^[1] ; Lorenzo,Buroni ^[1] ; Wei,Yuan ^[1] ; Alejandro,Athie ^[3] ; Teresa,Casals ^[3] ; Juliet,Carmichael ^[4] ; Daniel Nava,Rodrigues ^[1] ; Bora,Gurel ^[1] ; Pasquale,Rescigno ^[4] ; Jan,Rekowski ^[1] ; Jon,Welti ^[1] ; Ruth,Riisnaes ^[1] ; Veronica,Gil ^[1] ; Jian,Ning ^[1] ; Verena,Wagner ^[5] ; Irene,Casanova-Salas ^[3] ; Sarai,Cordoba ^[3] ; Natalia,Castro ^[3] ; Maria Dolores,Fenor de la Maza ^[4] ; George,Seed ^[1] ; Khobe,Chandran ^[4] ; Ana,Ferreira ^[1] ; Ines,Figueiredo ^[1] ; Claudia,Bertan ^[1] ; Diletta,Bianchini ^[4] ; Caterina,Aversa ^[4] ; Alec,Paschalis ^[4] ; Macarena,Gonzalez ^[6] ; Rafael,Morales-Barrera ^[6] ; Cristina,Suarez ^[6] ; Joan,Carles ^[6] ; Amanda,Swain ^[1] ; Adam,Sharp ^[4] ; Jesus,Gil ^[5] ; Violeta,Serra ^[2] ; Christopher,Lord ^[1] ; Suzanne,Carreira ^[1] ; Joaquin,Mateo ^[7] ; Johann S,de Bono ^[8]

作者单位： The Institute of Cancer Research, London, UK. ^[1] Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain; Vall d'Hebron Institute of Research (VHIR), Barcelona, Spain. ^[2] Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain. ^[3] The Institute of Cancer Research, London, UK; The Royal Marsden NHS Foundation Trust, London, UK. ^[4] MRC London Institute of Medical Sciences (LMS) and Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College, London, UK. ^[5] Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain; Vall d'Hebron University Hospital, Barcelona, Spain. ^[6] Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain; Vall d'Hebron University Hospital, Barcelona, Spain. Electronic address: jmateo@vhio.net. ^[7] The Institute of Cancer Research, London, UK; The Royal Marsden NHS Foundation Trust, London, UK. Electronic address: Johann.debono@icr.ac.uk. ^[8]

关键词 ATM ATR inhibition DNA damage response PARP inhibition Prostate cancer Synthetic lethality

医学主题词人类(Humans);男(雄)性(Male);肿瘤分期(Neoplasm Staging);前列腺肿瘤(Prostatic Neoplasms);回顾性研究(Retrospective Studies);肿瘤细胞, 培养的(Tumor Cells, Cultured)

DOI 10.1016/j.eururo.2020.10.029

PMID 33176972

发布时间 2025-05-30

基金项目

28647/CRUK_/Cancer Research UK/United Kingdom MC_U120085810/MRC_/Medical Research Council/United Kingdom

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交