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Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia.

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第一作者: Juliette,Roels
第一单位: Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.;Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
作者单位: Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.;Cancer Research Institute Ghent (CRIG), Ghent, Belgium. [1] Institute of Human Genetics, Polish Academy of Sciences, Poznań, Poland. [2] Department of Medical Biosciences, Umeå University, Umeå, Sweden. [3] Cancer Research Institute Ghent (CRIG), Ghent, Belgium.;Department of Diagnostic Sciences, Ghent University, Ghent, Belgium. [4] Department of Diagnostic Sciences, Ghent University, Ghent, Belgium. [5] Department of Pediatric Oncology, Hematology, and Immunology, University of Heidelberg, and Hopp Children's Cancer Center at NCT Heidelberg, Heidelberg, Germany.;Molecular Medicine Partnership Unit (MMPU), European Molecular Biology Laboratory (EMBL), University of Heidelberg, Heidelberg, Germany. [6] Laboratory of Protein Chemistry, Proteomics and Epigenetic Signaling (PPES) and Integrated Personalized and Precision Oncology Network (IPPON), Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium. [7] Cancer Research Institute Ghent (CRIG), Ghent, Belgium.;Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium. [8] Laboratory of Pharmaceutical Biotechnology, Ghent University, Ghent, Belgium. [9] Telethon Kids Cancer Centre, Telethon Kids Institute, University of Western Australia, Perth, Western Australia.;School of Pharmacy and Biomedical Sciences, Curtin University, Perth, Western Australia. [10] Department of Haematology, University College London Cancer Institute, London, England. [11] Metabolomics Expertise Center, VIB Center for Cancer Biology, Leuven, Belgium. [12] Center of Medical Genetics, University of Antwerp, Antwerp, Belgium. [13] Department of Pediatric Hematology, Oncology and Transplantology, Medical University of Lublin, Lublin, Poland. [14] Department of Pediatric Hematology and Oncology, Zabrze, Medical University of Silesia, Katowice, Poland. [15] Roudebush Veterans Affairs Medical Center and Indiana University School of Medicine, Indianapolis, Indiana. [16] Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.;Cancer Research Institute Ghent (CRIG), Ghent, Belgium.;Department of Diagnostic Sciences, Ghent University, Ghent, Belgium. [17] Australian Centre for Blood Diseases (ACBD), Monash University, Melbourne, Australia. [18] Department of Medical Biosciences, Umeå University, Umeå, Sweden.;Department of Clinical Microbiology, Umeå University, Umeå, Sweden. [19] Department of Biomolecular Medicine, Ghent University, Ghent, Belgium. pieter.vanvlierberghe@ugent.be.;Cancer Research Institute Ghent (CRIG), Ghent, Belgium. [20]
DOI 10.1158/2643-3230.BCD-20-0059
PMID 33179015
发布时间 2025-05-30
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Blood cancer discovery

Blood cancer discovery

2020年1卷3期

274-289页

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