Organic Selenium Reaches the Central Nervous System and Downmodulates Local Inflammation: A Complementary Therapy for Multiple Sclerosis?

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作者： Juliana Helena Dos Santos,de Toledo ^[1] ; Thais Fernanda de Campos,Fraga-Silva ^[1] ; Patrícia Aparecida,Borim ^[1] ; Larissa Ragozo Cardoso,de Oliveira ^[1] ; Evelyn da Silva,Oliveira ^[1] ; Larissa Lucena,Périco ^[2] ; Clélia Akiko,Hiruma-Lima ^[2] ; Adriana Aparecida Lopes,de Souza ^[3] ; Carlos Alberto Ferreira,de Oliveira ^[4] ; Pedro de Magalhães,Padilha ^[1] ; Marcos Felipe,Pinatto-Botelho ^[5] ; Alcindo Aparecido,Dos Santos ^[5] ; Alexandrina,Sartori ^[1] ; Sofia Fernanda Gonçalves,Zorzella-Pezavento ^[1]

作者单位： Department of Chemical and Biological Sciences, Institute of Biosciences, São Paulo State University (UNESP), Botucatu, Brazil. ^[1] Department of Structural and Functional Biology, São Paulo State University (UNESP), Institute of Biosciences, Botucatu, Brazil. ^[2] Veterinary Clinical Laboratory, School of Veterinary Medicine and Animal Science (FMVZ), São Paulo State University (UNESP), Botucatu, Brazil. ^[3] Department of Research and Development, Biorigin Company, Lençóis Paulista, Brazil. ^[4] LabSSeTe Department of Fundamental Chemistry, Institute of Chemistry, University of São Paulo (USP), São Paulo, Brazil. ^[5]

关键词 experimental autoimmune encephalomyelitis inflammasome microglia multiple sclerosis selenium