CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD<sup>+</sup> and NMN levels.

导出 LinkOut

翻译打印收藏纠错

第一作者： Claudia C S,Chini

第一单位： Signal Transduction and Molecular Nutrition Laboratory, Kogod Aging Center, Department of Anesthesiology and Perioperative Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA.

作者： Claudia C S,Chini ^[1] ; Thais R,Peclat ^[1] ; Gina M,Warner ^[1] ; Sonu,Kashyap ^[1] ; Jair Machado,Espindola-Netto ^[1] ; Guilherme C,de Oliveira ^[1] ; Lilian S,Gomez ^[1] ; Kelly A,Hogan ^[1] ; Mariana G,Tarragó ^[1] ; Amrutesh S,Puranik ^[2] ; Guillermo,Agorrody ^[1] ; Katie L,Thompson ^[1] ; Kevin,Dang ^[3] ; Starlynn,Clarke ^[3] ; Bennett G,Childs ^[4] ; Karina S,Kanamori ^[1] ; Micaela A,Witte ^[1] ; Paola,Vidal ^[1] ; Anna L,Kirkland ^[1] ; Marco,De Cecco ^[5] ; Karthikeyani,Chellappa ^[6] ; Melanie R,McReynolds ^[7] ; Connor,Jankowski ^[7] ; Tamara,Tchkonia ^[8] ; James L,Kirkland ^[8] ; John M,Sedivy ^[9] ; Jan M,van Deursen ^[4] ; Darren J,Baker ^[4] ; Wim,van Schooten ^[3] ; Joshua D,Rabinowitz ^[7] ; Joseph A,Baur ^[6] ; Eduardo N,Chini ^[10]

作者单位： Signal Transduction and Molecular Nutrition Laboratory, Kogod Aging Center, Department of Anesthesiology and Perioperative Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA. ^[1] Signal Transduction and Molecular Nutrition Laboratory, Kogod Aging Center, Department of Anesthesiology and Perioperative Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA.;Division of Rheumatology, Department of Medicine, NYU Langone Health, New York, NY, USA. ^[2] Teneobio, Newark, CA, USA. ^[3] Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, USA. ^[4] Center on the Biology of Aging and Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI, USA.;Astellas Institute for Regenerative Medicine, Marlborough, MA, USA. ^[5] Department of Physiology and Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. ^[6] Lewis-Sigler Institute for Integrative Genomics, Department of Chemistry, Princeton University, Princeton, NJ, USA. ^[7] Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA. ^[8] Center on the Biology of Aging and Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI, USA. ^[9] Signal Transduction and Molecular Nutrition Laboratory, Kogod Aging Center, Department of Anesthesiology and Perioperative Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA. chini.eduardo@mayo.edu. ^[10]

主题词脂肪细胞, 白色(Adipocytes, White);脂肪组织, 白色(Adipose Tissue, White);衰老(Aging);动物(Animals);骨髓移植(Bone Marrow Transplantation);HEK293细胞(HEK293 Cells);人类(Humans);炎症(Inflammation);肝(Liver);膜糖蛋白类(Membrane Glycoproteins);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);小鼠, 转基因(Mice, Transgenic);NAD(NAD);烟酰胺单核苷酸(Nicotinamide Mononucleotide);表型(Phenotype)

DOI 10.1038/s42255-020-00298-z

PMID 33199925

发布时间 2024-09-23

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交

浏览21

Nature metabolism

2020年2卷11期

1284-1304页

相似文献

中文期刊
外文期刊
学位论文
会议论文

检索历史清除

CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD<sup>+</sup> and NMN levels.

Nature metabolism

相似文献

Nature metabolism

相关期刊

参考文献：
指定格式：	NoteExpress EndNote RefWorks NoteFirst

检索历史 清除

CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD<sup>+</sup> and NMN levels.

Nature metabolism

相似文献

Nature metabolism

相关期刊

检索历史清除