Crystallographic structure of wild-type SARS-CoV-2 main protease acyl-enzyme intermediate with physiological C-terminal autoprocessing site.

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第一作者： Jaeyong,Lee

第一单位： Department of Biochemistry and Molecular Biology and Centre for Blood Research, The University of British Columbia, Vancouver, BC, Canada.;Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada.

作者： Jaeyong,Lee ^[1] ; Liam J,Worrall ^[2] ; Marija,Vuckovic ^[2] ; Federico I,Rosell ^[2] ; Francesco,Gentile ^[3] ; Anh-Tien,Ton ^[3] ; Nathanael A,Caveney ^[2] ; Fuqiang,Ban ^[3] ; Artem,Cherkasov ^[3] ; Mark,Paetzel ^[4] ; Natalie C J,Strynadka ^[5]

作者单位： Department of Biochemistry and Molecular Biology and Centre for Blood Research, The University of British Columbia, Vancouver, BC, Canada.;Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada. ^[1] Department of Biochemistry and Molecular Biology and Centre for Blood Research, The University of British Columbia, Vancouver, BC, Canada. ^[2] Vancouver Prostate Centre, The University of British Columbia, Vancouver, BC, Canada. ^[3] Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada. mpaetzel@sfu.ca. ^[4] Department of Biochemistry and Molecular Biology and Centre for Blood Research, The University of British Columbia, Vancouver, BC, Canada. ncjs@mail.ubc.ca. ^[5]