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Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth.

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第一作者: Ryan S,Roark
第一单位: Departments of Medicine and Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
作者单位: Departments of Medicine and Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. [1] Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.;Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA. [2] Laboratory of Molecular Medicine, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA. [3] Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. [4] Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA. [5] Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.;Departments of Immunology and Surgery, Duke University School of Medicine, Durham, NC 27710, USA. [6] Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.;Departments of Pediatrics and Immunology, Duke University School of Medicine, Durham, NC 27710, USA. [7] Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, NM 87545, USA. [8] Bioqual, Inc., Rockville, MD 20850, USA. [9] Department of Microbiology, Boston University School of Medicine, Boston, MA 02118, USA.;Department of Mathematics and Statistics, Boston University, Boston, MA 02215, USA. [10] Laboratory of Molecular Medicine, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.;Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA. [11] Departments of Medicine and Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. shawg@pennmedicine.upenn.edu. [12]
DOI 10.1126/science.abd2638
PMID 33214287
发布时间 2024-12-07
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