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Pre-depletion of TRBC1+ T cells promotes the therapeutic efficacy of anti-TRBC1 CAR-T for T-cell malignancies.

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第一作者: Chaoting,Zhang
第一单位: Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Laboratory of Biochemistry and Molecular Biology, Peking University Cancer Hospital & Institute, Beijing, 100142, China.
作者: Chaoting,Zhang [1] ; Heyilimu,Palashati [1] ; Zhuona,Rong [1] ; Ningjing,Lin [2] ; Luyan,Shen [1] ; Ying,Liu [3] ; Shance,Li [1] ; Bentong,Yu [4] ; Wenjun,Yang [5] ; Zheming,Lu [6]
作者单位: Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Laboratory of Biochemistry and Molecular Biology, Peking University Cancer Hospital & Institute, Beijing, 100142, China. [1] Key Laboratory of Carcinogenesis and Translational Research, Departments of Lymphoma, Radiology and Nuclear Medicine, Peking University Cancer Hospital and Institute, Beijing, 100142, China. [2] Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Laboratory of Genetics, Peking University Cancer Hospital & Institute, Beijing, 100142, China. [3] Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Laboratory of Biochemistry and Molecular Biology, Peking University Cancer Hospital & Institute, Beijing, 100142, China. yubentong@126.com. [4] Department of Thoracic Surgery, The First Affiliated Hospital of Nanchang University, Jiangxi, 330006, China. yubentong@126.com. [5] Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Laboratory of Biochemistry and Molecular Biology, Peking University Cancer Hospital & Institute, Beijing, 100142, China. ywj007@yeah.net. [6] Key Laboratory of Fertility Preservation and Maintenance, School of Basic Medicine and the General Hospital, Ningxia Medical University, Yinchuan, 750004, Ningxia, China. ywj007@yeah.net. [7] Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Laboratory of Biochemistry and Molecular Biology, Peking University Cancer Hospital & Institute, Beijing, 100142, China. luzheming@bjmu.edu.cn. [8]
DOI 10.1186/s12943-020-01282-7
PMID 33218364
发布时间 2021-08-03
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