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首页> Toxicology> Perfluoroheptanoic acid induces Leydig cell hyperplasia but inhibits spermatogenesis in rats after pubertal exposure.

Perfluoroheptanoic acid induces Leydig cell hyperplasia but inhibits spermatogenesis in rats after pubertal exposure.

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作者： Zengqiang,Li ^[1] ; Changchang,Li ^[1] ; Zina,Wen ^[2] ; Haoni,Yan ^[1] ; Cheng,Zou ^[1] ; Yang,Li ^[1] ; Lili,Tian ^[1] ; Zhen,Lei ^[3] ; Huitao,Li ^[1] ; Yiyan,Wang ^[1] ; Ying,Zhong ^[4] ; Ren-Shan,Ge ^[5]

作者单位： Department of Anesthesiology, Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325027, China. ^[1] Department of Anesthesiology, Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325027, China; Chengdu Xi'nan Gynecological Hospital, Chengdu, Sichuan, China. ^[2] Chengdu Xi'nan Gynecological Hospital, Chengdu, Sichuan, China. ^[3] Chengdu Xi'nan Gynecological Hospital, Chengdu, Sichuan, China. Electronic address: yzhong8@yahoo.com. ^[4] Department of Anesthesiology, Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325027, China. Electronic address: r_ge@yahoo.com. ^[5]

关键词 Immature Leydig cells PFHpA Perfluoroheptanoic acid Testosterone short-chain perfluoroalkyl substances

主题词年龄因素(Age Factors);动物(Animals);剂量效应关系, 药物(Dose-Response Relationship, Drug);氟碳化合物(Fluorocarbons);庚酸类(Heptanoic Acids);增生(Hyperplasia);莱迪希细胞(Leydig Cells);男(雄)性(Male);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);性成熟(Sexual Maturation);精子发生(Spermatogenesis)

DOI 10.1016/j.tox.2020.152633

PMID 33220336

发布时间 2021-12-04

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