Retinal capillary degeneration and blood-retinal barrier disruption in murine models of Alzheimer's disease.

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作者： Haoshen,Shi ^[1] ; Yosef,Koronyo ^[1] ; Dieu-Trang,Fuchs ^[1] ; Julia,Sheyn ^[1] ; Kolja,Wawrowsky ^[2] ; Shouri,Lahiri ^[3] ; Keith L,Black ^[1] ; Maya,Koronyo-Hamaoui ^[4]

作者单位： Department of Neurosurgery, Maxine Dunitz Neurosurgical Research Institute, Cedars-Sinai Medical Center, 127 S. San Vicente Blvd., Los Angeles, CA, 90048, USA. ^[1] Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA. ^[2] Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA. ^[3] Department of Neurosurgery, Maxine Dunitz Neurosurgical Research Institute, Cedars-Sinai Medical Center, 127 S. San Vicente Blvd., Los Angeles, CA, 90048, USA. maya.koronyo@csmc.edu. ^[4] Department of Biomedical Sciences, Division of Applied Cell Biology and Physiology, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA. maya.koronyo@csmc.edu. ^[5]

关键词 Dementia Neurodegeneration Neurological disease Ocular pathology Retinal blood vessels Tight junction

主题词阿尔茨海默病(Alzheimer Disease);淀粉样β蛋白前体(Amyloid beta-Protein Precursor);淀粉样变性(Amyloidosis);动物(Animals);血视网膜屏障(Blood-Retinal Barrier);毛细血管(Capillaries);毛细血管通透性(Capillary Permeability);疾病模型, 动物(Disease Models, Animal);人类(Humans);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);早老素1(Presenilin-1);受体, 血小板源生长因子β(Receptor, Platelet-Derived Growth Factor beta);视网膜血管(Retinal Vessels)

DOI 10.1186/s40478-020-01076-4

PMID 33228786

发布时间 2021-11-09

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Acta neuropathologica communications

2020年8卷1期

202页

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Retinal capillary degeneration and blood-retinal barrier disruption in murine models of Alzheimer's disease.

Acta neuropathologica communications

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Acta neuropathologica communications

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Retinal capillary degeneration and blood-retinal barrier disruption in murine models of Alzheimer's disease.

Acta neuropathologica communications

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Acta neuropathologica communications

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