An endogenous PI3K interactome promoting astrocyte-mediated neuroprotection identifies a novel association with RNA-binding protein ZC3H14.

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作者： Samih,Alqawlaq ^[1] ; Izhar,Livne-Bar ^[1] ; Declan,Williams ^[2] ; Joseph,D'Ercole ^[1] ; Sara W,Leung ^[3] ; Darren,Chan ^[1] ; Alessandra,Tuccitto ^[1] ; Alessandro,Datti ^[4] ; Jeffrey L,Wrana ^[4] ; Anita H,Corbett ^[3] ; Gerold,Schmitt-Ulms ^[2] ; Jeremy M,Sivak ^[5]

作者单位： Department of Vision Science, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada; Department of Ophthalmology and Vision Science, University of Toronto School of Medicine, Toronto, Ontario, Canada. ^[1] Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Ontario, Canada. ^[2] Department of Biology, Emory University, Atlanta, Georgia, USA. ^[3] Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada. ^[4] Department of Vision Science, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada; Department of Ophthalmology and Vision Science, University of Toronto School of Medicine, Toronto, Ontario, Canada. Electronic address: jsivak@uhnres.utoronto.ca. ^[5]

关键词 PDGF PI3K ZC3h14 astrocyte interactome neuroprotection

主题词星形细胞(Astrocytes);DNA结合蛋白质类(DNA-Binding Proteins);免疫沉淀法(Immunoprecipitation);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);Poly(A)结合蛋白质类(Poly(A)-Binding Proteins);RNA结合蛋白质类(RNA-Binding Proteins);串联质谱法(Tandem Mass Spectrometry)

DOI 10.1074/jbc.RA120.015389

PMID 33234594

发布时间 2024-02-29

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The Journal of biological chemistry

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An endogenous PI3K interactome promoting astrocyte-mediated neuroprotection identifies a novel association with RNA-binding protein ZC3H14.

The Journal of biological chemistry

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An endogenous PI3K interactome promoting astrocyte-mediated neuroprotection identifies a novel association with RNA-binding protein ZC3H14.

The Journal of biological chemistry

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The Journal of biological chemistry

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