The disubstituted adamantyl derivative LW1564 inhibits the growth of cancer cells by targeting mitochondrial respiration and reducing hypoxia-inducible factor (HIF)-1α accumulation.

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第一作者： Inhyub,Kim

第一单位： Personalized Genomic Medicine Research Center, KRIBB, Daejeon, 34141, Korea.;Department of Functional Genomics, University of Science and Technology, Daejeon, 34141, Korea.

作者： Inhyub,Kim ^[1] ; Minkyoung,Kim ^[2] ; Min Kyung,Park ^[3] ; Ravi,Naik ^[2] ; Jae Hyung,Park ^[2] ; Bo-Kyung,Kim ^[4] ; Yongseok,Choi ^[5] ; Kwan Young,Chang ^[6] ; Misun,Won ^[7] ; Hyun Seung,Ban ^[8] ; Kyeong,Lee ^[9]

作者单位： Personalized Genomic Medicine Research Center, KRIBB, Daejeon, 34141, Korea.;Department of Functional Genomics, University of Science and Technology, Daejeon, 34141, Korea. ^[1] College of Pharmacy, Dongguk University-Seoul, Goyang, 10326, Korea. ^[2] Personalized Genomic Medicine Research Center, KRIBB, Daejeon, 34141, Korea.;College of Pharmacy, Dongguk University-Seoul, Goyang, 10326, Korea. ^[3] Personalized Genomic Medicine Research Center, KRIBB, Daejeon, 34141, Korea. ^[4] College of Life Sciences and Biotechnology, Korea University, Seoul, 02841, Korea. ^[5] OneCureGEN Co., Ltd, Seoul, Korea. ^[6] Personalized Genomic Medicine Research Center, KRIBB, Daejeon, 34141, Korea. misun@kribb.re.kr.;Department of Functional Genomics, University of Science and Technology, Daejeon, 34141, Korea. misun@kribb.re.kr. ^[7] Biotherapeutics Translational Research Center, KRIBB, Daejeon, 34141, Korea. banhs@kribb.re.kr. ^[8] College of Pharmacy, Dongguk University-Seoul, Goyang, 10326, Korea. kaylee@dongguk.edu. ^[9]