18F-Fluciclovine PET metabolic imaging reveals prostate cancer tumour heterogeneity associated with disease resistance to androgen deprivation therapy.

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作者： Gaurav,Malviya ^[1] ; Rachana,Patel ^[1] ; Mark,Salji ^[1] ; Rafael S,Martinez ^[2] ; Peter,Repiscak ^[3] ; Ernest,Mui ^[1] ; Susan,Champion ^[2] ; Agata,Mrowinska ^[1] ; Emma,Johnson ^[1] ; Maha,AlRasheedi ^[2] ; Sally,Pimlott ^[4] ; David,Lewis ^[1] ; Hing Y,Leung ^[1]

作者单位： Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK. ^[1] Institute of Cancer Sciences, University of Glasgow, Glasgow, UK. ^[2] Department of Urology, NHS Greater Glasgow and Clyde, Glasgow, UK. ^[3] West of Scotland PET Centre, NHS Greater Glasgow and Clyde, Glasgow, UK. ^[4] Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK. d.lewis@beatson.gla.ac.uk. ^[5] Institute of Cancer Sciences, University of Glasgow, Glasgow, UK. d.lewis@beatson.gla.ac.uk. ^[6] Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK. h.leung@beatson.gla.ac.uk. ^[7] Institute of Cancer Sciences, University of Glasgow, Glasgow, UK. h.leung@beatson.gla.ac.uk. ^[8] Department of Urology, NHS Greater Glasgow and Clyde, Glasgow, UK. h.leung@beatson.gla.ac.uk. ^[9]

关键词 18F-Fluciclovine (FACBC)Amino acid transporter Castration-resistant prostate cancer Metabolic imaging Tumour heterogeneity

DOI 10.1186/s13550-020-00728-9

PMID 33237350

发布时间 2024-02-10

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