Induced pluripotent stem cells derived from the developing striatum as a potential donor source for cell replacement therapy for Huntington disease.

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第一作者： Narawadee,Choompoo

第一单位： Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, UK; Department of Anatomy, Faculty of Medical Science, Naresuan University, Phisanulok, Thailand.

作者： Narawadee,Choompoo ^[1] ; Oliver J M,Bartley ^[2] ; Sophie V,Precious ^[2] ; Ngoc-Nga,Vinh ^[2] ; Christian,Schnell ^[2] ; Ana,Garcia ^[2] ; Victoria H,Roberton ^[2] ; Nigel M,Williams ^[3] ; Paul J,Kemp ^[2] ; Claire M,Kelly ^[4] ; Anne E,Rosser ^[5]

作者单位： Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, UK; Department of Anatomy, Faculty of Medical Science, Naresuan University, Phisanulok, Thailand. ^[1] Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, UK. ^[2] MRC Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Cardiff University, Cardiff, UK. ^[3] Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, UK; Cardiff School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, UK. ^[4] Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, UK; MRC Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Cardiff University, Cardiff, UK; Wales Brain Repair and Intracranial Neurotherapeutics Unit, School of Medicine, Cardiff University, Cardiff, UK. Electronic address: rosserae@cf.ac.uk. ^[5]

关键词 Huntington disease cell therapy epigenetic memory fetal tissue iPSC striatal differentiation

主题词细胞分化(Cell Differentiation);纹状体(Corpus Striatum);人类(Humans);杭廷顿病(Huntington Disease);诱导多能干细胞(Induced Pluripotent Stem Cells)

DOI 10.1016/j.jcyt.2020.06.001

PMID 33246883

发布时间 2022-03-24

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