Case Study: Prolonged Infectious SARS-CoV-2 Shedding from an Asymptomatic Immunocompromised Individual with Cancer.

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作者： Victoria A,Avanzato ^[1] ; M Jeremiah,Matson ^[2] ; Stephanie N,Seifert ^[3] ; Rhys,Pryce ^[4] ; Brandi N,Williamson ^[3] ; Sarah L,Anzick ^[5] ; Kent,Barbian ^[5] ; Seth D,Judson ^[6] ; Elizabeth R,Fischer ^[5] ; Craig,Martens ^[5] ; Thomas A,Bowden ^[4] ; Emmie,de Wit ^[3] ; Francis X,Riedo ^[7] ; Vincent J,Munster ^[8]

作者单位： Laboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK. ^[1] Laboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA; Marshall University Joan C. Edwards School of Medicine, Huntington, WV 25701, USA. ^[2] Laboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA. ^[3] Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK. ^[4] Research Technologies Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA. ^[5] Department of Medicine, University of Washington, Seattle, WA 98195, USA. ^[6] EvergreenHealth, Kirkland, WA 98034, USA. Electronic address: fxriedo@evergreenhealthcare.org. ^[7] Laboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA. Electronic address: vincent.munster@nih.gov. ^[8]

关键词 COVID-19 SARS-CoV-2 asymptometic chronic lymphocytic leukemia convalescent plasma immunocompromised infectious virus long-term shedding within host evolution

主题词老年人(Aged);抗体, 病毒(Antibodies, Viral);普通可变性免疫缺陷(Common Variable Immunodeficiency);女(雌)性(Female);人类(Humans);白血病, 淋巴细胞, 慢性, B细胞(Leukemia, Lymphocytic, Chronic, B-Cell);呼吸道感染(Respiratory Tract Infections)

DOI 10.1016/j.cell.2020.10.049

PMID 33248470

发布时间 2024-02-12

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