Charting a DNA Repair Roadmap for Immunoglobulin Class Switch Recombination.

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第一作者： Tannishtha,Saha

第一单位： Laboratory of Genome Diversification and Integrity, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin 13125, Germany.

作者： Tannishtha,Saha ^[1] ; Devakumar,Sundaravinayagam ^[2] ; Michela,Di Virgilio ^[3]

作者单位： Laboratory of Genome Diversification and Integrity, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin 13125, Germany. ^[1] Laboratory of Genome Diversification and Integrity, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin 13125, Germany. Electronic address: Devakumar.Sundaravinayagam@mdc-berlin.de. ^[2] Laboratory of Genome Diversification and Integrity, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin 13125, Germany; Charité-Universitätsmedizin Berlin, Berlin 10117, Germany. Electronic address: michela.divirgilio@mdc-berlin.de. ^[3]

关键词 DNA double-strand breaks alternative end joining antibody-mediated responses class switch recombination immunoglobulin heavy chain locus nonhomologous end joining

主题词 B-淋巴细胞(B-Lymphocytes);胞苷脱氨酶(Cytidine Deaminase);DNA断裂, 双链(DNA Breaks, Double-Stranded);DNA修复(DNA Repair);免疫球蛋白类别转换(Immunoglobulin Class Switching);免疫球蛋白重链(Immunoglobulin Heavy Chains)

DOI 10.1016/j.tibs.2020.10.005

PMID 33250286

发布时间 2021-09-17

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