Crosslink among phosphatidylinositol-3 kinase/Akt, PTEN and STAT-5A signaling pathways post liposomal galactomannan hepatocellular carcinoma therapy.

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作者： Rehab M,Abdel-Megeed ^[1] ; Sameh H,Abd El-Alim ^[2] ; Azza F,Arafa ^[1] ; Azza A,Matloub ^[3] ; Abd El Razik H,Farrag ^[4] ; Asmaa B,Darwish ^[2] ; Abdel-Hamid Z,Abdel-Hamid ^[1] ; Mai O,Kadry ^[1]

作者单位： Therapeutic Chemistry Department, National Research Centre, El-Buhouth St., Cairo, 12622, Egypt. ^[1] Pharmaceutical Technology Department, National Research Centre, El-Buhouth St., Cairo, 12622, Egypt. ^[2] Pharmacognosy D Department, National Research Centre, El-Buhouth St., Cairo, 12622, Egypt. ^[3] Pathology Department, National Research Centre, El-Buhouth St., Cairo, 12622, Egypt. ^[4]

关键词 AFP, α-fetoprotein ALP, alkaline phasphatase ALT, alanine aminotransferase AST, aspartate aminotransferase Akt, serine/threonine kinase Bad, Bcl-2-associated death promoter C. gilliesii, Caesalpinia gilliesii CCl4, carbon tetrachloride DDs, drug-delivery systems DEN, diethylnitrosamine FOXO1, fork-head box protein O1 GM, galactomannan GSH, glutathione GSK3, glycogen synthase kinase GST, glutathione S-transferase HCC, hepatocellular carcinoma Hepatocellular carcinoma LDDs, liposomal drug-delivery systems LPs, liposomes Liposomal galactomannan PI3K, phosphoinositide 3-kinase PI3K/Akt PIP2, phosphatidylinositol bisphosphate PIP3, phosphatidylinositol trisphosphate PTEN PTEN, phosphatase and tensin homolog STAT 5A STAT-5A, signal transducer and activator of transcription-5A TEM, transmission electron microscopy VS, vesicle size

DOI 10.1016/j.toxrep.2020.10.018

PMID 33251120

发布时间 2020-12-01

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Toxicology reports

2020年7卷

1531-1541页

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Crosslink among phosphatidylinositol-3 kinase/Akt, PTEN and STAT-5A signaling pathways post liposomal galactomannan hepatocellular carcinoma therapy.

Toxicology reports

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Toxicology reports

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Crosslink among phosphatidylinositol-3 kinase/Akt, PTEN and STAT-5A signaling pathways post liposomal galactomannan hepatocellular carcinoma therapy.

Toxicology reports

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Toxicology reports

相关期刊

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