Bioinspired channeled, rhBMP-2-coated β-TCP scaffolds with embedded autologous vascular bundles for increased vascularization and osteogenesis of prefabricated tissue-engineered bone.

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作者： Miao,Zhou ^[1] ; Xiaobin,Yang ^[2] ; Shuyi,Li ^[2] ; Kausik,Kapat ^[2] ; Kai,Guo ^[2] ; Fidel Hugo,Perera ^[3] ; Li,Qian ^[4] ; Pedro,Miranda ^[5] ; Yuejuan,Che ^[6]

作者单位： Key Laboratory of Oral Medicine, Guangzhou Institute of Oral Disease, Affiliated Stomatology Hospital of Guangzhou Medical University, Guangzhou 510140, China. Electronic address: zhm1000@gzhmu.edu.cn. ^[1] Key Laboratory of Oral Medicine, Guangzhou Institute of Oral Disease, Affiliated Stomatology Hospital of Guangzhou Medical University, Guangzhou 510140, China. ^[2] Departamento de Ingeniería Mecánica, Energética y de los Materiales, Universidad de Extremadura, Escuela de Ingenierías Industriales, Avda. de Elvas s/n, 06006 Badajoz, Spain. ^[3] Hangzhou Jiu Yuan Gene Engineering Co., Ltd., Hangzhou 3100018, China. ^[4] Departamento de Ingeniería Mecánica, Energética y de los Materiales, Universidad de Extremadura, Escuela de Ingenierías Industriales, Avda. de Elvas s/n, 06006 Badajoz, Spain. Electronic address: pmiranda@unex.es. ^[5] Department of Anaesthesia, Sun Yet-sen Memorial Hospital, Sun Yet-sen University, Yanjiang Road 120, Guangzhou 510120, China. Electronic address: cheyj@mail.sysu.edu.cn. ^[6]

关键词 Biomimetic Bone graft substitute Multi-channeled scaffold Osteogenesis Vascularization

主题词磷酸钙类(Calcium Phosphates);骨生成(Osteogenesis);组织工程(Tissue Engineering);组织支架(Tissue Scaffolds)

DOI 10.1016/j.msec.2020.111389

PMID 33254995

发布时间 2021-05-14

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