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Lactoferrin-dual drug nanoconjugate: Synergistic anti-tumor efficacy of docetaxel and the NF-κB inhibitor celastrol.

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第一作者: Mona A,Abdelmoneem
第一单位: Cancer Nanotechnology Research Laboratory (CNRL), Faculty of Pharmacy, Alexandria University, Alexandria, Egypt; Department of Pharmaceutics, Faculty of Pharmacy, Damanhur University, Damanhur, Egypt; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Harvard-MIT Division of Health Sciences & Technology (HST), Cambridge, MA 02139, USA.
作者单位: Cancer Nanotechnology Research Laboratory (CNRL), Faculty of Pharmacy, Alexandria University, Alexandria, Egypt; Department of Pharmaceutics, Faculty of Pharmacy, Damanhur University, Damanhur, Egypt; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Harvard-MIT Division of Health Sciences & Technology (HST), Cambridge, MA 02139, USA. [1] Cancer Nanotechnology Research Laboratory (CNRL), Faculty of Pharmacy, Alexandria University, Alexandria, Egypt; Graduate school of Pharmaceutical Sciences, Hokkaido University, Japan. [2] Cancer Nanotechnology Research Laboratory (CNRL), Faculty of Pharmacy, Alexandria University, Alexandria, Egypt; Department of Chemistry, Faculty of Science, Alexandria University, Alexandria 21321, Egypt. Electronic address: sh.n.khattab@gmail.com. [3] Cancer Nanotechnology Research Laboratory (CNRL), Faculty of Pharmacy, Alexandria University, Alexandria, Egypt; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Damanhur University, Damanhur, Egypt. [4] Cancer Nanotechnology Research Laboratory (CNRL), Faculty of Pharmacy, Alexandria University, Alexandria, Egypt; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt; Pharmacy Program, Allied Health Department, College of Health and Sport Sciences, University of Bahrain, P.O. Box 32038, Bahrain. [5] Department of Biochemistry, Faculty of Science, Alexandria University, Alexandria 21511, Egypt. [6] Cancer Nanotechnology Research Laboratory (CNRL), Faculty of Pharmacy, Alexandria University, Alexandria, Egypt; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt. [7] Cancer Nanotechnology Research Laboratory (CNRL), Faculty of Pharmacy, Alexandria University, Alexandria, Egypt; Department of Industrial Pharmacy, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt. [8] School of Chemistry and Physics, University of KwaZulu-Natal, Durban 4001, South Africa; CIBER-BBN, Networking Centre on Bioengineering Biomaterials and Nanomedicine, Barcelona Science Park, Barcelona 08028, Spain; Department of Organic Chemistry, University of Barcelona, Barcelona 08028, Spain. [9] Cancer Nanotechnology Research Laboratory (CNRL), Faculty of Pharmacy, Alexandria University, Alexandria, Egypt; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Harvard-MIT Division of Health Sciences & Technology (HST), Cambridge, MA 02139, USA; Department of Industrial Pharmacy, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt. Electronic address: aelzoghby@bwh.harvard.edu. [10]
DOI 10.1016/j.msec.2020.111422
PMID 33255023
发布时间 2021-05-14
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