第一作者:
Carol C L,Chen
第一单位:
Department of Human Genetics, McGill University, Montreal, QC H3A 0C7, Canada.
作者:
Carol C L,Chen [1]
;
Shriya,Deshmukh [2]
;
Selin,Jessa [3]
;
Djihad,Hadjadj [1]
;
Véronique,Lisi [1]
;
Augusto Faria,Andrade [1]
;
Damien,Faury [4]
;
Wajih,Jawhar [1]
;
Rola,Dali [5]
;
Hiromichi,Suzuki [6]
;
Manav,Pathania [7]
;
Deli,A [8]
;
Frank,Dubois [9]
;
Eleanor,Woodward [9]
;
Steven,Hébert [10]
;
Marie,Coutelier [10]
;
Jason,Karamchandani [11]
;
Steffen,Albrecht [12]
;
Sebastian,Brandner [13]
;
Nicolas,De Jay [10]
;
Tenzin,Gayden [1]
;
Andrea,Bajic [1]
;
Ashot S,Harutyunyan [4]
;
Dylan M,Marchione [14]
;
Leonie G,Mikael [4]
;
Nikoleta,Juretic [4]
;
Michele,Zeinieh [1]
;
Caterina,Russo [4]
;
Nicola,Maestro [15]
;
Angelia V,Bassenden [16]
;
Peter,Hauser [17]
;
József,Virga [18]
;
Laszlo,Bognar [19]
;
Almos,Klekner [19]
;
Michal,Zapotocky [20]
;
Ales,Vicha [20]
;
Lenka,Krskova [21]
;
Katerina,Vanova [20]
;
Josef,Zamecnik [21]
;
David,Sumerauer [20]
;
Paul G,Ekert [22]
;
David S,Ziegler [23]
;
Benjamin,Ellezam [24]
;
Mariella G,Filbin [25]
;
Mathieu,Blanchette [26]
;
Jordan R,Hansford [22]
;
Dong-Anh,Khuong-Quang [27]
;
Albert M,Berghuis [16]
;
Alexander G,Weil [28]
;
Benjamin A,Garcia [14]
;
Livia,Garzia [29]
;
Stephen C,Mack [30]
;
Rameen,Beroukhim [31]
;
Keith L,Ligon [32]
;
Michael D,Taylor [6]
;
Pratiti,Bandopadhayay [33]
;
Christoph,Kramm [34]
;
Stefan M,Pfister [35]
;
Andrey,Korshunov [36]
;
Dominik,Sturm [37]
;
David T W,Jones [38]
;
Paolo,Salomoni [39]
;
Claudia L,Kleinman [40]
;
Nada,Jabado [41]
作者单位:
Department of Human Genetics, McGill University, Montreal, QC H3A 0C7, Canada.
[1]
Division of Experimental Medicine, Department of Medicine, McGill University, Montreal, QC H4A 3J1, Canada.
[2]
Quantitative Life Sciences, McGill University, Montreal, QC H3A 2A7, Canada; Lady Davis Research Institute, Jewish General Hospital, Montreal, QC H3T 1E2, Canada.
[3]
Department of Pediatrics, McGill University, and The Research Institute of the McGill University Health Centre, Montreal, QC H4A 3J1, Canada.
[4]
Canadian Centre for Computational Genomics, McGill University, Montreal, QC H3A 0E9, Canada.
[5]
Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
[6]
Department of Oncology and The Milner Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; CRUK Children's Brain Tumour Centre of Excellence, University of Cambridge, Cambridge CB2 0RE, UK.
[7]
Nuclear Function in CNS Pathophysiology, German Center for Neurodegenerative Diseases (DZNE), Bonn 53127, Germany.
[8]
Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, 02215, USA.
[9]
Department of Human Genetics, McGill University, Montreal, QC H3A 0C7, Canada; Lady Davis Research Institute, Jewish General Hospital, Montreal, QC H3T 1E2, Canada.
[10]
Department of Pathology, Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada.
[11]
Department of Pathology, Montreal Children's Hospital, McGill University Health Centre, Montreal, QC H4A 3J1, Canada.
[12]
UCL Queen Square Institute of Neurology, London WC1N 3BG, UK.
[13]
Department of Biochemistry and Biophysics and Penn Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6073, USA.
[14]
Department of Oncology and The Milner Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK.
[15]
Department of Biochemistry, McGill University, Montreal, QC H3A 1A3, Canada.
[16]
Second Department of Paediatrics, Semmelweis University, Budapest 1094, Hungary.
[17]
Department of Neurosurgery, University of Debrecen, Debrecen 4032, Hungary; Department of Oncology, Faculty of Medicine, University of Debrecen, Debrecen 4032, Hungary.
[18]
Department of Neurosurgery, University of Debrecen, Debrecen 4032, Hungary.
[19]
Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague 150 06, Czech Republic.
[20]
Department of Pathology and Molecular Medicine, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague 150 06, Czech Republic.
[21]
Children's Cancer Center, The Royal Children's Hospital; Murdoch Children's Research Institute; Department of Pediatrics, University of Melbourne, Parkville, VIC 3052, Australia.
[22]
Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW 2031, Australia; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW 2052, Australia.
[23]
Department of Pathology, Centre Hospitalier Universitaire Sainte-Justine, Université de Montréal, Montréal, QC H3T 1C5, Canada.
[24]
Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA 02215, USA.
[25]
School of Computer Science, McGill University, Montreal, QC H3A 2A7, Canada.
[26]
Children's Cancer Center, The Royal Children's Hospital; and Murdoch Children's Research Institute; Parkville, VIC 3052, Australia.
[27]
Department of Pediatric Neurosurgery, Centre Hospitalier Universitaire Sainte-Justine, Université de Montréal, Montréal, QC H3T 1C5, Canada.
[28]
Cancer Research Program, The Research Institute of the McGill University Health Centre, Montreal, QC H4A 3J1, Canada; Division of Orthopedic Surgery, Faculty of Surgery, McGill University, Montreal, QC H3G 1A4, Canada.
[29]
Department of Pediatrics, Division of Hematology and Oncology, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
[30]
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215-5450, USA; Broad Institute of MIT and Harvard, Boston, MA 02142, USA.
[31]
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215-5450, USA; Department of Pathology, Boston Children's Hospital and Brigham and Women's Hospital, Harvard Medical School, and Department of Oncologic Pathology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
[32]
Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, 02215, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215-5450, USA; Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.
[33]
Division of Pediatric Hematology and Oncology, University Medical Center Goettingen, Goettingen 37075, Germany.
[34]
Hopp Children's Cancer Center Heidelberg (KiTZ) and Department of Pediatric Oncology, Hematology and Immunology, University Hospital Heidelberg, Heidelberg 69120, Germany; Division of Pediatric Neurooncology, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg 69120, Germany; Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg 69120, Germany.
[35]
Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg 69120, Germany; Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg 69120, Germany.
[36]
Division of Pediatric Hematology and Oncology, University Medical Center Goettingen, Goettingen 37075, Germany; Pediatric Glioma Research Group, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
[37]
Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg 69120, Germany; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg 69120, Germany.
[38]
Department of Oncology and The Milner Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Nuclear Function in CNS Pathophysiology, German Center for Neurodegenerative Diseases (DZNE), Bonn 53127, Germany.
[39]
Department of Human Genetics, McGill University, Montreal, QC H3A 0C7, Canada; Lady Davis Research Institute, Jewish General Hospital, Montreal, QC H3T 1E2, Canada. Electronic address: claudia.kleinman@mcgill.ca.
[40]
Department of Human Genetics, McGill University, Montreal, QC H3A 0C7, Canada; Division of Experimental Medicine, Department of Medicine, McGill University, Montreal, QC H4A 3J1, Canada; Department of Pediatrics, McGill University, and The Research Institute of the McGill University Health Centre, Montreal, QC H4A 3J1, Canada. Electronic address: nada.jabado@mcgill.ca.
[41]
主题词
动物(Animals);星形细胞(Astrocytes);脑肿瘤(Brain Neoplasms);细胞谱系(Cell Lineage);染色质(Chromatin);胚胎, 哺乳动物(Embryo, Mammalian);后成说, 遗传(Epigenesis, Genetic);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因沉默(Gene Silencing);神经胶质瘤(Glioma);组蛋白类(Histones);中间神经元(Interneurons);赖氨酸(Lysine);小鼠, 近交C57BL(Mice, Inbred C57BL);模型, 生物学(Models, Biological);突变(Mutation);神经干细胞(Neural Stem Cells);少突神经胶质(Oligodendroglia);启动区, 遗传(Promoter Regions, Genetic);前脑(Prosencephalon);受体, 血小板源生长因子α(Receptor, Platelet-Derived Growth Factor alpha);转录, 遗传(Transcription, Genetic)
DOI
10.1016/j.cell.2020.11.012
PMID
33259802
发布时间
2021-12-11
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Cell
Cell
1617-1633.e22页
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