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The Nucleosome Remodeling and Deacetylase Complex Has an Asymmetric, Dynamic, and Modular Architecture.

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第一作者： Jason K K,Low

第一单位： School of Life and Environmental Sciences, University of Sydney, NSW, Australia. Electronic address: jason.low@sydney.edu.au.

作者： Jason K K,Low ^[1] ; Ana P G,Silva ^[2] ; Mehdi,Sharifi Tabar ^[2] ; Mario,Torrado ^[2] ; Sarah R,Webb ^[2] ; Benjamin L,Parker ^[2] ; Maryam,Sana ^[2] ; Callum,Smits ^[3] ; Jason W,Schmidberger ^[2] ; Lou,Brillault ^[4] ; Matthew J,Jackman ^[4] ; David C,Williams ^[5] ; Gerd A,Blobel ^[6] ; Sandra B,Hake ^[7] ; Nicholas E,Shepherd ^[2] ; Michael J,Landsberg ^[8] ; Joel P,Mackay ^[9]

作者单位： School of Life and Environmental Sciences, University of Sydney, NSW, Australia. Electronic address: jason.low@sydney.edu.au. ^[1] School of Life and Environmental Sciences, University of Sydney, NSW, Australia. ^[2] Sydney, NSW, Australia. ^[3] School of Chemistry and Molecular Biosciences, University of Queensland, QLD, Australia. ^[4] Dept of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, NC, USA. ^[5] The Division of Hematology, Children's Hospital of Philadelphia, and the Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. ^[6] Institute for Genetics, FB08 Biology, Justus-Liebig-University Giessen, Giessen, Germany. ^[7] School of Chemistry and Molecular Biosciences, University of Queensland, QLD, Australia. Electronic address: m.landsberg@uq.edu.au. ^[8] School of Life and Environmental Sciences, University of Sydney, NSW, Australia. Electronic address: joel.mackay@sydney.edu.au. ^[9]

关键词 DIA-MS EM NuRD PWWP2A cross-linking MS electron microscopy gene regulation nucleosome remodeling

医学主题词基因表达调控(Gene Expression Regulation);组蛋白脱乙酰基酶类(Histone Deacetylases);人类(Humans);模型, 分子(Models, Molecular);核小体(Nucleosomes)

DOI 10.1016/j.celrep.2020.108450

PMID 33264611

发布时间 2022-03-16

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