Translational adaptation to heat stress is mediated by RNA 5-methylcytosine in Caenorhabditis elegans.

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作者： Isabela Cunha,Navarro ^[1] ; Francesca,Tuorto ^[2] ; David,Jordan ^[1] ; Carine,Legrand ^[3] ; Jonathan,Price ^[1] ; Fabian,Braukmann ^[1] ; Alan G,Hendrick ^[4] ; Alper,Akay ^[5] ; Annika,Kotter ^[6] ; Mark,Helm ^[6] ; Frank,Lyko ^[3] ; Eric A,Miska ^[7]

作者单位： Gurdon Institute, University of Cambridge, Cambridge, UK.;Department of Genetics, University of Cambridge, Cambridge, UK. ^[1] Division of Epigenetics, DKFZ-ZMBH Alliance, German Cancer Research Center, Heidelberg, Germany.;Division of Biochemistry, Mannheim Institute for Innate Immunoscience (MI3), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.;Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, Heidelberg, Germany. ^[2] Division of Epigenetics, DKFZ-ZMBH Alliance, German Cancer Research Center, Heidelberg, Germany. ^[3] STORM Therapeutics Limited, Babraham Research Campus, Cambridge, UK. ^[4] Gurdon Institute, University of Cambridge, Cambridge, UK.;Department of Genetics, University of Cambridge, Cambridge, UK.;School of Biological Sciences, University of East Anglia, Norwich, UK. ^[5] Institute of Pharmacy and Biochemistry, Johannes Gutenberg-University Mainz, Mainz, Germany. ^[6] Gurdon Institute, University of Cambridge, Cambridge, UK.;Department of Genetics, University of Cambridge, Cambridge, UK.;Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK. ^[7]

关键词 Caenorhabditis elegans 5-methylcytosine NSUN RNA modifications translation efficiency