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首页> Expert opinion on biological therapy> <i>HLA-Cw6</i> and other HLA-C alleles, as well as <i>MICB-DT, DDX58,</i> and <i>TYK2</i> genetic variants associate with optimal response to anti-IL-17A treatment in patients with psoriasis.

<i>HLA-Cw6</i> and other HLA-C alleles, as well as <i>MICB-DT, DDX58,</i> and <i>TYK2</i> genetic variants associate with optimal response to anti-IL-17A treatment in patients with psoriasis.

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作者： Martina,Morelli ^[1] ; Marco,Galluzzo ^[2] ; Stefania,Madonna ^[3] ; Claudia,Scarponi ^[1] ; Giovanni Luca,Scaglione ^[1] ; Tiziana,Galluccio ^[1] ; Marco,Andreani ^[4] ; Sabatino,Pallotta ^[4] ; Giampiero,Girolomoni ^[1] ; Luca,Bianchi ^[2] ; Marina,Talamonti ^[5] ; Cristina,Albanesi ^[5]

作者单位： Laboratory of Experimental Immunology, IDI-IRCCS , Rome, Italy. ^[1] Section of Dermatology, Department of Medicine, University of Verona , Verona, Italy. ^[2] Department of Experimental Medicine, University of Rome "Tor Vergata" , Rome, Italy. ^[3] Department of Oncohematology and Cell and Gene Therapy, IRCCS Bambin Gesù Pediatric Hospital, Laboratory of Immunogenetics and Transplant , Rome, Italy. ^[4] Department of Systems Medicine, University of Rome "Tor Vergata" , Rome, Italy. ^[5]

关键词 HLA-Cw6 Psoriasis SNPs anti-IL-17A pharmacogenomics secukinumab

主题词等位基因(Alleles);队列研究(Cohort Studies);HLA-C抗原(HLA-C Antigens);人类(Humans);银屑病(Psoriasis);受体, 免疫(Receptors, Immunologic);TYK2激酶(TYK2 Kinase);治疗结果(Treatment Outcome)

DOI 10.1080/14712598.2021.1862082

PMID 33297781

发布时间 2023-12-13

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Expert opinion on biological therapy

Expert opinion on biological therapy

2021年21卷2期

259-270页

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