Opportunities and challenges of delivering digital clinical trials: lessons learned from a randomised controlled trial of an online behavioural intervention for children and young people.

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作者： Charlotte L,Hall ^[1] ; Charlotte,Sanderson ^[2] ; Beverly J,Brown ^[3] ; Per,Andrén ^[4] ; Sophie,Bennett ^[2] ; Liam R,Chamberlain ^[3] ; E Bethan,Davies ^[3] ; Kareem,Khan ^[3] ; Natalie,Kouzoupi ^[2] ; David,Mataix-Cols ^[4] ; Caitlin,McKenzie ^[3] ; Tara,Murphy ^[2] ; Mark,Townsend ^[5] ; Chris,Hollis ^[3] ; Elizabeth,Murray ^[6]

作者单位： NIHR MindTech Medtech Co-operative, School of Medicine, Division of Psychiatry and Applied Psychology, Institute of Mental Health, University of Nottingham Innovation Park, Triumph Road, Nottingham, UK. charlotte.hall@nottingham.ac.uk. ^[1] University College London, Great Ormond Street Institute of Child Health, London, UK. ^[2] NIHR MindTech Medtech Co-operative, School of Medicine, Division of Psychiatry and Applied Psychology, Institute of Mental Health, University of Nottingham Innovation Park, Triumph Road, Nottingham, UK. ^[3] Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden. ^[4] National Institute for Health Research, University of Southampton, Alpha House, Enterprise Road, Southampton, UK. ^[5] Research Department of Primary Care and Population Health, University College London, London, UK. ^[6]

关键词 Chronic tic disorder Internet Online Randomised controlled trials Recruitment Research design Retention Tourette syndrome