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Genome-wide association study of asthma exacerbations despite inhaled corticosteroid use.

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作者单位: Research Unit, Hospital Universitario N.S. de Candelaria, Universidad de La Laguna, Santa Cruz de Tenerife, Spain. [1] Genomics and Health Group, Dept of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, San Cristóbal de La Laguna, Spain. [2] Dept of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands. [3] Division of Pharmacoepidemiology and Clinical Pharmacology, Faculty of Science, Utrecht University, Utrecht, The Netherlands. [4] Dept of Paediatric Respiratory Medicine and Allergy, Emma's Children Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands. [5] The Channing Division of Network Medicine, Dept of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. [6] Dept of Biological Sciences, National University of Singapore, Singapore, Singapore. [7] MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. [8] CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain. [9] Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, UK. [10] Breathomix B.V., El Reeuwijk, The Netherlands. [11] Center for Human Molecular Genetics and Pharmacogenomics, Faculty of Medicine, University of Maribor, Maribor, Slovenia. [12] Laboratory for Biochemistry, Molecular Biology and Genomics, Faculty for Chemistry and Chemical Engineering, University of Maribor, Maribor, Slovenia. [13] Academic Dept of Paediatrics, Brighton and Sussex Medical School, Royal Alexandra Children's Hospital, Brighton, UK. [14] Escola Nacional de Saúde Pública, Lisboa, Portugal. [15] Dept of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands. [16] Dept of Paediatric Pneumology and Allergy, University Children's Hospital Regensburg (KUNO), Regensburg, Germany. [17] Dept of Human Genetics, Hannover Medical School, Hannover, Germany. [18] Dept of Clinic Epidemiology and Biostatistics, Research Unit, Hospital Universitario N.S. de Candelaria, Gerencia de Atención Primaria, Santa Cruz de Tenerife, Spain. [19] Dept of Paediatrics, University Medical Centre Maribor, Maribor, Slovenia. [20] Population Pharmacogenetics Group, Biomedical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK. [21] Dept of Medicine, University of California, San Francisco, San Francisco, CA, USA. [22] Division of Paediatric Respiratory Medicine, Hospital Universitario Donostia, San Sebastián, Spain. [23] Dept of Paediatrics, University of the Basque Country (UPV/EHU), San Sebastián, Spain. [24] Dept of Clinical Sciences and Education Södersjukhuset, Karolinska Institutet and Sachs' Children's Hospital, Stockholm, Sweden. [25] Dept of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK. [26] Dept of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA. [27] Dept of Women's and Children's Health, University of Liverpool, Liverpool, UK. [28] Alder Hey Children's Hospital, Liverpool, UK. [29] Institute of Environmental Medicine, Karolinska Institutet, Solna, Sweden. [30] Division of Pulmonary and Critical Care Medicine, Dept of Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA, USA. [31] Child Health, University of Aberdeen, Aberdeen, UK. [32] Genomics Division, Instituto Tecnológico y de Energías Renovables (ITER), Santa Cruz de Tenerife, Spain. [33] Instituto de Tecnologías Biomédicas (ITB), Universidad de La Laguna, San Cristóbal de La Laguna, Spain. [34] Research Unit, Hospital Universitario N.S. de Candelaria, Universidad de La Laguna, Santa Cruz de Tenerife, Spain mdelpino@ull.edu.es. [35] These authors contributed equally to this work. [36]
DOI 10.1183/13993003.03388-2020
PMID 33303529
发布时间 2023-11-15
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