作者:
Andre C,Kalil [1]
;
Thomas F,Patterson [1]
;
Aneesh K,Mehta [1]
;
Kay M,Tomashek [1]
;
Cameron R,Wolfe [1]
;
Varduhi,Ghazaryan [1]
;
Vincent C,Marconi [1]
;
Guillermo M,Ruiz-Palacios [1]
;
Lanny,Hsieh [1]
;
Susan,Kline [1]
;
Victor,Tapson [1]
;
Nicole M,Iovine [1]
;
Mamta K,Jain [1]
;
Daniel A,Sweeney [1]
;
Hana M,El Sahly [1]
;
Angela R,Branche [1]
;
Justino,Regalado Pineda [1]
;
David C,Lye [1]
;
Uriel,Sandkovsky [1]
;
Anne F,Luetkemeyer [1]
;
Stuart H,Cohen [1]
;
Robert W,Finberg [1]
;
Patrick E H,Jackson [1]
;
Babafemi,Taiwo [1]
;
Catharine I,Paules [2]
;
Henry,Arguinchona ;
Nathaniel,Erdmann ;
Neera,Ahuja ;
Maria,Frank ;
Myoung-Don,Oh ;
Eu-Suk,Kim ;
Seow Y,Tan ;
Richard A,Mularski ;
Henrik,Nielsen ;
Philip O,Ponce ;
Barbara S,Taylor ;
LuAnn,Larson ;
Nadine G,Rouphael ;
Youssef,Saklawi ;
Valeria D,Cantos ;
Emily R,Ko ;
John J,Engemann ;
Alpesh N,Amin ;
Miki,Watanabe ;
Joanne,Billings ;
Marie-Carmelle,Elie ;
Richard T,Davey ;
Timothy H,Burgess ;
Jennifer,Ferreira ;
Michelle,Green ;
Mat,Makowski ;
Anabela,Cardoso ;
Stephanie,de Bono ;
Tyler,Bonnett ;
Michael,Proschan ;
Gregory A,Deye ;
Walla,Dempsey ;
Seema U,Nayak ;
Lori E,Dodd ;
John H,Beigel ;
ACTT-2 Study Group Members
作者单位:
From the University of Nebraska Medical Center, Omaha (A.C.K., L.L.); University of Texas Health San Antonio, University Health, and the South Texas Veterans Health Care System, San Antonio (T.F.P., P.O.P., B.S.T.), UT Southwestern Medical Center, Parkland Health and Hospital System (M.K.J.) and Baylor Scott and White Health (U.S.), Dallas, and Baylor College of Medicine, Houston (H.M.E.S.) - all in Texas; Emory University (A.K.M., N.G.R., Y.S., V.C.M., V.D.C.) and Grady Memorial Hospital (V.D.C.), Atlanta, and Atlanta Veterans Affairs Medical Center, Decatur (V.C.M.) - both in Georgia; the National Institute of Allergy and Infectious Diseases, National Institutes of Health (K.M.T., V.G., R.T.D., M.P., G.A.D., W.D., S.U.N., L.E.D., J.H.B.), and the Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences (T.H.B.), Bethesda, and Emmes (J.F., M.G., M.M.) and Clinical Monitoring Research Program Directorate, Frederick National Laboratory (T.B.), Rockville - both in Maryland; Duke University, Durham, NC (C.R.W., E.R.K., J.J.E.); Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, (G.M.R.-P.) and Instituto Nacional de Enfermedades Respiratorias (J.R.P.), Mexico City; University of California Irvine, Irvine (L.H., A.N.A., M.W.), Cedars-Sinai Medical Center, Los Angeles (V.T.), University of California, San Diego, La Jolla (D.A.S.), University of California, San Francisco, San Francisco (A.F.L.), University of California, Davis, Davis (S.H.C.), and Stanford University, Stanford (N.A.) - all in California; University of Minnesota Medical School, Minneapolis (S.K., J.B.); University of Florida, Gainesville (N.M.I., M.-C.E.); University of Rochester, Rochester, NY (A.R.B.); National Center for Infectious Diseases, Tan Tock Seng Hospital, Lee Kong Chian School of Medicine, and Yong Loo Lin School of Medicine (D.C.L.), and Changi General Hospital (S.Y.T.), Singapore; University of Massachusetts Medical School, Worcester (R.W.F.); University of Virginia, Charlottesville (P.E.H.J.); Northwestern University, Chicago (B.T.); Penn State Health Milton S. Hershey Medical Center, Hershey, PA (C.I.P.); Providence Sacred Heart Medical Center, Spokane, WA (H.A.); University of Alabama at Birmingham, Birmingham (N.E.); Denver Health and Hospital Authority, Denver (M.F.); Seoul National University Hospital, Seoul (M.O.), and Seoul National University Bundang Hospital, Seongnam (E.-S.K.) - both in South Korea; Kaiser Permanente Northwest, Portland, OR (R.A.M.); Aalborg University Hospital, Aalborg, Denmark (H.N.); and Eli Lilly, Indianapolis (A.C., S.B.).
[1]
From the University of Nebraska Medical Center, Omaha (A.C.K., L.L.); University of Texas Health San Antonio, University Health, and the South Texas Veterans Health Care System, San Antonio (T.F.P., P.O.P., B.S.T.), UT Southwestern Medical Center, Parkland Health and Hospital System (M.K.J.) and Baylor Scott and White Health (U.S.), Dallas, and Baylor College of Medicine, Houston (H.M.E.S.) - all in Texas; Emory University (A.K.M., N.G.R., Y.S., V.C.M., V.D.C.) and Grady Memorial Hospital (V.D.C.), Atlanta, and Atlanta Veterans Affairs Medical Center, Decatur (V.C.M.) - both in Georgia; the National Institute of Allergy and Infectious Diseases, National Institutes of Health (K.M.T., V.G., R.T.D., M.P., G.A.D., W.D., S.U.N., L.E.D., J.H.B.), and the Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences (T.H.B.), Bethesda, and Emmes (J.F., M.G., M.M.) and Clinical Monitoring Research Program Directorate, Frederick National Laboratory (T.B.), Rockville - both in Maryland; Duke University, Durham, NC (C.R.W., E.R.K., J.J.E.); Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, (G.M.R.-P.) and Instituto Nacional de Enfermedades Respiratorias (J.R.P.), Mexico City; University of California Irvine, Irvine (L.H., A.N.A., M.W.), Cedars-Sinai Medical Center, Los Angeles (V.T.), University of California, San Diego, La Jolla (D.A.S.), University of California, San Francisco, San Francisco (A.F.L.), University of California, Davis, Davis (S.H.C.), and Stanford University, Stanford (N.A.) - all in California; University of Minnesota Medical School, Minneapolis (S.K., J.B.); University of Florida, Gainesville (N.M.I., M.-C.E.); University of Rochester, Rochester, NY (A.R.B.); National Center for Infectious Diseases, Tan Tock Seng Hospital, Lee Kong Chian School of Medicine, and Yong Loo Lin School of Medicine (D.C.L.), and Changi General Hospital (S.Y.T.), Singapore; University of Massachusetts Medical School, Worcester (R.W.F.); University of Virginia, Charlottesville (P.E.H.J.); Northwestern University, Chicago (B.T.); Penn State Health Milton S. Hershey Medical Center, Hershey, PA (C.I.P.); Providence Sacred Heart Medical Center, Sp
[2]
主题词
腺苷一磷酸(Adenosine Monophosphate);成年人(Adult);老年人(Aged);丙氨酸(Alanine);抗病毒药(Antiviral Agents);吖丁啶类(Azetidines);双盲法(Double-Blind Method);药物疗法, 联合(Drug Therapy, Combination);女(雌)性(Female);医院死亡率(Hospital Mortality);住院(Hospitalization);人类(Humans);男(雄)性(Male);中年人(Middle Aged);氧吸入疗法(Oxygen Inhalation Therapy);嘌呤类(Purines);吡唑类(Pyrazoles);呼吸, 人工(Respiration, Artificial);磺胺类(Sulfonamides);治疗结果(Treatment Outcome)
DOI
10.1056/NEJMoa2031994
PMID
33306283
发布时间
2023-10-15
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The New England journal of medicine
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