The Pharmacodynamic-Toxicodynamic Relationship of AUC and <i>C</i><sub>max</sub> in Vancomycin-Induced Kidney Injury in an Animal Model.

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作者： Sean N,Avedissian ^[1] ; Gwendolyn,Pais ^[2] ; Jiajun,Liu ^[3] ; J Nicholas,O'Donnell ^[4] ; Thomas P,Lodise ^[3] ; Michael,Neely ^[4] ; Walter C,Prozialeck ^[5] ; Peter C,Lamar ^[5] ; Leighton,Becher ^[6] ; Marc H,Scheetz ^[7]

作者单位： Antiviral Pharmacology Laboratory, University of Nebraska Medical Center Center for Drug Discovery, University of Nebraska Medical Center, Omaha, Nebraska, USA. ^[1] University of Nebraska Medical Center, College of Pharmacy, Omaha, Nebraska, USA. ^[2] Department of Pharmacy Practice, Chicago College of Pharmacy, Midwestern University, Downers Grove, Illinois, USA. ^[3] Midwestern University Chicago College of Pharmacy Center of Pharmacometric Excellence, Downers Grove, Illinois, USA. ^[4] Department of Pharmacy Practice, Albany College of Pharmacy and Health Sciences, Albany, New York, USA. ^[5] Children's Hospital Los Angeles and University of Southern California, Los Angeles, California, USA. ^[6] College of Graduate Studies, Midwestern University, Downers Grove, Illinois, USA. ^[7] Department of Pharmacy Practice, Chicago College of Pharmacy, Midwestern University, Downers Grove, Illinois, USA mschee@midwestern.edu. ^[8]

关键词 pharmacodynamics pharmacokinetics pharmacology rat toxicodynamics vancomycin