换一批Hydrogen sulfide inhibits aortic valve calcification in heart via regulating RUNX2 by NF-κB, a link between inflammation and mineralization.
第一作者：
Katalin,Éva Sikura
第一单位：
Division of Nephrology, Department of Medicine, Faculty of Medicine, University of Debrecen, 4012 Debrecen, Hungary.;HAS-UD Vascular Biology and Myocardial Pathophysiology Research Group, Hungarian Academy of Sciences, Debrecen, Hungary.
作者：
关键词
AP72AP72, 4-methoxyphenyl piperidinylphosphinodithioc acidAS, stenotic aortic valve with calcificationAortic valveApoE-/-, apolipoprotein E-deficient miceApolipoprotein E knockout miceCAVDCAVD, calcific aortic valve diseaseCBS, Cystathionine beta-synthaseCSE, Cystathionine gamma-lyaseH2SHAV, healthy aortic valve from suicide patientsIL-1β, interleukin-1βInflammationNF-κB, nuclear factor-κBSTED, Stimulated Emission Depletion NanoscopyTNF-α, tumor necrosis factor αVIC, valvular interstitial cellscVIC, control healthy valve interstitial cellsmHAV, healthy mouse aortic valvemVIC, mouse valvular interstitial cells
DOI
10.1016/j.jare.2020.07.005
PMID
33318875
发布时间
2025-05-30
- 浏览1
Journal of advanced research
2021年27卷
165-176页
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