A biaryl-linked tripeptide from Planomonospora reveals a widespread class of minimal RiPP gene clusters.

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第一作者： Mitja M,Zdouc

第一单位： Naicons Srl., Viale Ortles 22/4, 20139 Milano, Italy; Swammerdam Institute for Life Sciences, University of Amsterdam, Science Park 904, Amsterdam, XH 1098, the Netherlands. Electronic address: mzdouc@naicons.com.

作者： Mitja M,Zdouc ^[1] ; Mohammad M,Alanjary ^[2] ; Guadalupe S,Zarazúa ^[3] ; Sonia I,Maffioli ^[4] ; Max,Crüsemann ^[3] ; Marnix H,Medema ^[2] ; Stefano,Donadio ^[4] ; Margherita,Sosio ^[5]

作者单位： Naicons Srl., Viale Ortles 22/4, 20139 Milano, Italy; Swammerdam Institute for Life Sciences, University of Amsterdam, Science Park 904, Amsterdam, XH 1098, the Netherlands. Electronic address: mzdouc@naicons.com. ^[1] Bioinformatics Group, Wageningen University, Droevendaalsesteeg 1, Wageningen, PB 6708, the Netherlands. ^[2] Institut für Pharmazeutische Biologie, Rheinische Friedrich-Wilhelms-Universität, Nußallee 6, Bonn 53115, Germany. ^[3] Naicons Srl., Viale Ortles 22/4, 20139 Milano, Italy. ^[4] Naicons Srl., Viale Ortles 22/4, 20139 Milano, Italy. Electronic address: msosio@naicons.com. ^[5]

关键词 RiPPs actinomycetes biaryls heterologous expression minimal BGC phylogenomics

主题词放线细菌纲(Actinobacteria);生物制品(Biological Products);多基因族(Multigene Family);寡肽类(Oligopeptides);蛋白质构象(Protein Conformation);蛋白质加工, 转译后(Protein Processing, Post-Translational)

DOI 10.1016/j.chembiol.2020.11.009

PMID 33321099

发布时间 2021-11-10

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Cell chemical biology

2021年28卷5期

733-739.e4页

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A biaryl-linked tripeptide from Planomonospora reveals a widespread class of minimal RiPP gene clusters.

Cell chemical biology

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A biaryl-linked tripeptide from Planomonospora reveals a widespread class of minimal RiPP gene clusters.

Cell chemical biology

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Cell chemical biology

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