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Comprehensive Mutational and Phenotypic Characterization of New Metastatic Cutaneous Squamous Cell Carcinoma Cell Lines Reveal Novel Drug Susceptibilities.

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第一作者： Jay,Perry

第一单位： Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.;Illawarra Health & Medical Research Institute, Wollongong, NSW 2522, Australia.;CONCERT Translational Cancer Research Centre, Liverpool, NSW 2170, Australia.

作者： Jay,Perry ^[1] ; Bruce,Ashford ^[2] ; Amarinder Singh,Thind ^[3] ; Marie-Emilie,Gauthier ^[4] ; Elahe,Minaei ^[1] ; Gretel,Major ^[5] ; Narayanan Gopalakrishna,Iyer ^[6] ; Ruta,Gupta ^[7] ; Jonathan,Clark ^[8] ; Marie,Ranson ^[9]

作者单位： Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.;Illawarra Health & Medical Research Institute, Wollongong, NSW 2522, Australia.;CONCERT Translational Cancer Research Centre, Liverpool, NSW 2170, Australia. ^[1] Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.;Illawarra Health & Medical Research Institute, Wollongong, NSW 2522, Australia.;CONCERT Translational Cancer Research Centre, Liverpool, NSW 2170, Australia.;Sydney Head and Neck Cancer Institute, Chris O'Brien Lifehouse, Camperdown, NSW 2050, Australia.;School of Medicine, University of Wollongong, Wollongong, NSW 2522, Australia. ^[2] Illawarra Health & Medical Research Institute, Wollongong, NSW 2522, Australia.;School of Medicine, University of Wollongong, Wollongong, NSW 2522, Australia. ^[3] Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia. ^[4] Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.;Illawarra Health & Medical Research Institute, Wollongong, NSW 2522, Australia. ^[5] Department of Surgical Oncology, National Cancer Centre Singapore, Singapore 169610, Singapore. ^[6] Sydney Head and Neck Cancer Institute, Chris O'Brien Lifehouse, Camperdown, NSW 2050, Australia.;Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, NSW Health Pathology, Camperdown, NSW 2050, Australia. ^[7] Sydney Head and Neck Cancer Institute, Chris O'Brien Lifehouse, Camperdown, NSW 2050, Australia. ^[8] Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia.;Illawarra Health & Medical Research Institute, Wollongong, NSW 2522, Australia.;CONCERT Translational Cancer Research Centre, Liverpool, NSW 2170, Australia.;Sydney Head and Neck Cancer Institute, Chris O'Brien Lifehouse, Camperdown, NSW 2050, Australia. ^[9]

关键词 PI3K WGS cSCC cancer cell culture gene expression metastasis skin cancer ultraviolet xenograft