The protozoan parasite <i>Toxoplasma gondii</i> encodes a gamut of phosphodiesterases during its lytic cycle in human cells.
第一作者:
Kim Chi,Vo
第一单位:
Department of Molecular Parasitology, Institute of Biology, Faculty of Life Sciences, Humboldt University, Berlin, Germany.
作者:
关键词
3′IT, 3′-insertional taggingAC, adenylate cyclaseApicomplexaBradyzoiteCOS, crossover sequenceCRISPR, clustered regularly interspaced short palindromic repeatsEES, entero-epithelial stagesFPKM, fragments per kilobase of exon model per millionGC, guanylate cyclaseGMQE, Global Model Quality EstimationHFF, human foreskin fibroblastHXGPRT, hypoxanthine-xanthine-guanine phosphoribosyltransferaseIMC, inner membrane complexLytic cycleMAEBL, merozoite adhesive erythrocytic binding ligandMOI, multiplicity of infectionOCRE, octamer repeatPDE, phosphodiesterasePKA, protein kinase APKG, protein kinase GPM, plasma membraneQMEAN, Quality Model Energy AnalysisTachyzoitecAMP and cGMP signalingsgRNA, single guide RNAsmHA, spaghetti monster-HA
DOI
10.1016/j.csbj.2020.11.024
PMID
33335684
发布时间
2020-12-19
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