Expression of Oncolytic Adenovirus-Encoded RNAi Molecules Is Most Effective in a pri-miRNA Precursor Format.

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第一作者： Tereza,Brachtlova

第一单位： Department of Medical Oncology, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam Infection & Immunity Institute, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands.

作者： Tereza,Brachtlova ^[1] ; Jan-Willem,van Ginkel ^[2] ; Mark J,Luinenburg ^[2] ; Renée X,de Menezes ^[3] ; Danijela,Koppers-Lalic ^[4] ; D Michiel,Pegtel ^[3] ; Wenliang,Dong ^[5] ; Tanja D,de Gruijl ^[2] ; Victor W,van Beusechem ^[1]

作者单位： Department of Medical Oncology, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam Infection & Immunity Institute, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands. ^[1] ORCA Therapeutics B.V., 1081 HV Amsterdam, the Netherlands. ^[2] Department of Neurosurgery, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands. ^[3] Department of Epidemiology and Biostatistics, Amsterdam UMC, Vrije Universiteit Amsterdam, Netherlands Bioinformatics Center, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands. ^[4] Department of Pathology, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands. ^[5]

关键词 gene knockdown gene silencing oncolytic immunotherapy oncolytic virus

DOI 10.1016/j.omto.2020.10.012

PMID 33335978

发布时间 2020-12-19

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Molecular therapy oncolytics

2020年19卷

332-343页

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Expression of Oncolytic Adenovirus-Encoded RNAi Molecules Is Most Effective in a pri-miRNA Precursor Format.

Molecular therapy oncolytics

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Expression of Oncolytic Adenovirus-Encoded RNAi Molecules Is Most Effective in a pri-miRNA Precursor Format.

Molecular therapy oncolytics

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Molecular therapy oncolytics

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