换一批Oleanolic acid exerts neuroprotective effects in subarachnoid hemorrhage rats through SIRT1-mediated HMGB1 deacetylation.
第一作者：
Yuwei,Han
第一单位：
Department of Neurosurgery, General Hospital of Northern Theater Command, Shenyang, China; China Medical University, Shenyang, China.
作者：
医学主题词
乙酰化作用(Acetylation);动物(Animals);消炎药(Anti-Inflammatory Agents);细胞凋亡(Apoptosis);血脑屏障(Blood-Brain Barrier);脑(Brain);脑水肿(Brain Edema);毛细血管通透性(Capillary Permeability);疾病模型, 动物(Disease Models, Animal);HMGB1蛋白质(HMGB1 Protein);男(雄)性(Male);神经保护药(Neuroprotective Agents);齐墩果酸(Oleanolic Acid);蛋白质加工, 转译后(Protein Processing, Post-Translational);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);信号传导(Signal Transduction);抗衰老酶1(Sirtuin 1);蛛网膜下腔出血(Subarachnoid Hemorrhage);大鼠(Rats)
DOI
10.1016/j.ejphar.2020.173811
PMID
33345851
发布时间
2024-02-26
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